Microwave assisted synthesis of spiro heterocyclic systems: A Review

Pankaj Khanna, Leena Khanna, Sean J. Thomas, Abdullah M. Asiri, Siva Shankar Panda

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Background: Microwave irradiation has emerged as a useful synthetic strategy for chemists and drug developers due to enhanced yields, regioselectivity, and faster reaction times. One area of importance in its practice has been the design of spiro compounds, which possess great interest on account of their natural occurrence and medicinal capabilities. The increasingly large number of these scaffolds and unlimited amount of methodologies utilized in their preparation have made them good candidates for the microwave assisted approach. Conclusion: Therefore, this review emphasizes the use of microwave irradiation in the synthesis of spiro heterocyclic compounds.

Original languageEnglish (US)
Pages (from-to)67-84
Number of pages18
JournalCurrent Organic Chemistry
Volume22
Issue number1
DOIs
StatePublished - Jan 1 2018

Fingerprint

Microwave irradiation
Spiro Compounds
Microwaves
Heterocyclic Compounds
Regioselectivity
Scaffolds
Pharmaceutical Preparations

Keywords

  • Green synthesis
  • Heterocycles
  • Microwave
  • Spiro compounds

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Microwave assisted synthesis of spiro heterocyclic systems : A Review. / Khanna, Pankaj; Khanna, Leena; Thomas, Sean J.; Asiri, Abdullah M.; Panda, Siva Shankar.

In: Current Organic Chemistry, Vol. 22, No. 1, 01.01.2018, p. 67-84.

Research output: Contribution to journalReview article

Khanna, Pankaj ; Khanna, Leena ; Thomas, Sean J. ; Asiri, Abdullah M. ; Panda, Siva Shankar. / Microwave assisted synthesis of spiro heterocyclic systems : A Review. In: Current Organic Chemistry. 2018 ; Vol. 22, No. 1. pp. 67-84.
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