Migration of intradural epidermoid matrix

Embryologic implications

Stilianos E Kountakis, C. Y.Joseph Chang, William B. Gormley, Fernando R. Cabral

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The migratory behavior of acquired cholesteatoma matrices (those arising from the tympanic membrane) has been described previously. This tissue is derived embryologically from the first branchial groove and represents the only migratory epithelium arising from the branchial groove system. If the matrix from a cerebellopontine angle (CPA) epidermoid tumor exhibits migratory behavior similar to that of acquired cholesteatomas, a first branchial groove site of origin for CPA epidermoids would be supported. Intradural CPA epidermoid cells were grown in α-minimum essential medium. The cultures were examined daily, and cell mass migration rates were measured. It was observed that intradural epidermoid tumor matrix harvested from the CPA exhibited migration in vitro. Its migratory properties were indistinguishable from those of acquired cholesteatomas, which are embryologically derived from the first branchial groove. These data support the theory that purely intradural epidermoids are derived from cells of the first branchial groove.

Original languageEnglish (US)
Pages (from-to)170-173
Number of pages4
JournalOtolaryngology - Head and Neck Surgery
Volume123
Issue number3
DOIs
StatePublished - Jan 1 2000
Externally publishedYes

Fingerprint

Branchial Region
Cerebellopontine Angle
Cholesteatoma
Tympanic Membrane
Acoustic Neuroma
Cell Movement
Epithelium
Neoplasms

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

Cite this

Migration of intradural epidermoid matrix : Embryologic implications. / Kountakis, Stilianos E; Chang, C. Y.Joseph; Gormley, William B.; Cabral, Fernando R.

In: Otolaryngology - Head and Neck Surgery, Vol. 123, No. 3, 01.01.2000, p. 170-173.

Research output: Contribution to journalArticle

Kountakis, Stilianos E ; Chang, C. Y.Joseph ; Gormley, William B. ; Cabral, Fernando R. / Migration of intradural epidermoid matrix : Embryologic implications. In: Otolaryngology - Head and Neck Surgery. 2000 ; Vol. 123, No. 3. pp. 170-173.
@article{33972ec8071e4d948e11e19302bb200c,
title = "Migration of intradural epidermoid matrix: Embryologic implications",
abstract = "The migratory behavior of acquired cholesteatoma matrices (those arising from the tympanic membrane) has been described previously. This tissue is derived embryologically from the first branchial groove and represents the only migratory epithelium arising from the branchial groove system. If the matrix from a cerebellopontine angle (CPA) epidermoid tumor exhibits migratory behavior similar to that of acquired cholesteatomas, a first branchial groove site of origin for CPA epidermoids would be supported. Intradural CPA epidermoid cells were grown in α-minimum essential medium. The cultures were examined daily, and cell mass migration rates were measured. It was observed that intradural epidermoid tumor matrix harvested from the CPA exhibited migration in vitro. Its migratory properties were indistinguishable from those of acquired cholesteatomas, which are embryologically derived from the first branchial groove. These data support the theory that purely intradural epidermoids are derived from cells of the first branchial groove.",
author = "Kountakis, {Stilianos E} and Chang, {C. Y.Joseph} and Gormley, {William B.} and Cabral, {Fernando R.}",
year = "2000",
month = "1",
day = "1",
doi = "10.1067/mhn.2000.107518",
language = "English (US)",
volume = "123",
pages = "170--173",
journal = "Otolaryngology - Head and Neck Surgery (United States)",
issn = "0194-5998",
publisher = "Mosby Inc.",
number = "3",

}

TY - JOUR

T1 - Migration of intradural epidermoid matrix

T2 - Embryologic implications

AU - Kountakis, Stilianos E

AU - Chang, C. Y.Joseph

AU - Gormley, William B.

AU - Cabral, Fernando R.

PY - 2000/1/1

Y1 - 2000/1/1

N2 - The migratory behavior of acquired cholesteatoma matrices (those arising from the tympanic membrane) has been described previously. This tissue is derived embryologically from the first branchial groove and represents the only migratory epithelium arising from the branchial groove system. If the matrix from a cerebellopontine angle (CPA) epidermoid tumor exhibits migratory behavior similar to that of acquired cholesteatomas, a first branchial groove site of origin for CPA epidermoids would be supported. Intradural CPA epidermoid cells were grown in α-minimum essential medium. The cultures were examined daily, and cell mass migration rates were measured. It was observed that intradural epidermoid tumor matrix harvested from the CPA exhibited migration in vitro. Its migratory properties were indistinguishable from those of acquired cholesteatomas, which are embryologically derived from the first branchial groove. These data support the theory that purely intradural epidermoids are derived from cells of the first branchial groove.

AB - The migratory behavior of acquired cholesteatoma matrices (those arising from the tympanic membrane) has been described previously. This tissue is derived embryologically from the first branchial groove and represents the only migratory epithelium arising from the branchial groove system. If the matrix from a cerebellopontine angle (CPA) epidermoid tumor exhibits migratory behavior similar to that of acquired cholesteatomas, a first branchial groove site of origin for CPA epidermoids would be supported. Intradural CPA epidermoid cells were grown in α-minimum essential medium. The cultures were examined daily, and cell mass migration rates were measured. It was observed that intradural epidermoid tumor matrix harvested from the CPA exhibited migration in vitro. Its migratory properties were indistinguishable from those of acquired cholesteatomas, which are embryologically derived from the first branchial groove. These data support the theory that purely intradural epidermoids are derived from cells of the first branchial groove.

UR - http://www.scopus.com/inward/record.url?scp=0033817842&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033817842&partnerID=8YFLogxK

U2 - 10.1067/mhn.2000.107518

DO - 10.1067/mhn.2000.107518

M3 - Article

VL - 123

SP - 170

EP - 173

JO - Otolaryngology - Head and Neck Surgery (United States)

JF - Otolaryngology - Head and Neck Surgery (United States)

SN - 0194-5998

IS - 3

ER -