Mitochondria and peroxisomes: Are the 'Big Brother' and the 'Little Sister' closer than assumed?

Michael Schrader, Yisang Yoon

Research output: Contribution to journalReview article

97 Scopus citations

Abstract

Mitochondria and peroxisomes are essential subcellular organelles in mammals. Despite obvious differences, both organelles display certain morphological and functional similarities. Recent studies have elucidated that these highly dynamic and plastic organelles share components of their division machinery. Mitochondria and peroxisomes are metabolically linked organelles, which are cooperating and cross-talking. This review addresses the dynamics and division of mitochondria and peroxisomes as well as their functional similarities to provide insight as to why these organelles share the fission machinery in evolutionary aspects.

Original languageEnglish (US)
Pages (from-to)1105-1114
Number of pages10
JournalBioEssays
Volume29
Issue number11
DOIs
Publication statusPublished - Nov 1 2007
Externally publishedYes

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ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Biochemistry
  • Cell Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Agricultural and Biological Sciences (miscellaneous)
  • Plant Science

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