A Model-Based Systems Engineering (MBSE) framework using Object-Process Methodology (OPM) is developed and implemented for civil transport aircraft design with dynamic landing constraints. The foundations of the framework integrate the aircraft system development life cycle processes into a holistic MBSE model, incorporating into it the specific aircraft dynamic loads model-based design (MBD) domain. Using this framework, we also perform model-based requirements analysis, validation and verification. The model parameters set is governed by a unified format used for both the MBSE and MBD domains. The resulting model enables aircraft design processes to be formalized at different development stages, adding value to the MBSE and MBD practices by integrating and streamlining them into a holistic system development process.