TY - JOUR
T1 - Molecular, spatial, and field epidemiology suggesting TB transmission in community, not hospital, Gaborone, Botswana
AU - French Research Group on Epidemiology of Human Spongiform Encephalopathies
AU - Surie, Diya
AU - Fane, Othusitse
AU - Finlay, Alyssa
AU - Ogopotse, Matsiri
AU - Tobias, James L.
AU - Click, Eleanor S.
AU - Modongo, Chawangwa
AU - Zetola, Nicola M.
AU - Moonan, Patrick K.
AU - Oeltmann, John E.
AU - Basotli, Joyce
AU - Bile, Ebi
AU - Boyd, Rosanna
AU - Cowger, Victoria
AU - Dima, Mbatshi
AU - Gwebe-Nyirenda, Sambayawo
AU - Caiphus, Cynthia
AU - Katlholo, Thandi
AU - Serumola, Christopher
AU - Tamuhla, Tsaone
AU - Thamae, Goitseone
AU - Zimba, Onani
AU - Khumongwana, Pilara
AU - Ramogale, Kitso
AU - Shin, Sanghuk
AU - Shepherd, James
N1 - Funding Information:
We are grateful to the TB patients and their families for participating in this study. We thank the district health team and recruitment and retention officers who helped us coordinate with and contact patients. We are indebted to the Botswana National Tuberculosis Program and Botswana Ministry of Health for their partnership in this effort. We also thank the following persons for their thoughtful reviews of this manuscript: Benjamin Silk, Thomas Navin, Laura Podewils, Colleen Scott, and Carla Winston. This work was supported by the National Institutes of Health (grant R01AI097045; principal investigator: N.M.Z.) and the United States President’s Emergency Plan for AIDS Relief. Dr. Surie is an Epidemic Intelligence Service officer in the Division of Global HIV and TB, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia. Her primary research interests are molecular epidemiology and tuberculosis and HIV co-infection.
Publisher Copyright:
© 2017, Centers for Disease Control and Prevention (CDC). All rights reserved.
PY - 2017/3
Y1 - 2017/3
N2 - During 2012-2015, 10 of 24 patients infected with matching genotypes of Mycobacterium tuberculosis received care at the same hospital in Gaborone, Botswana. Nosocomial transmission was initially suspected, but we discovered plausible sites of community transmission for 20 (95%) of 21 interviewed patients. Active case-finding at these sites could halt ongoing transmission.
AB - During 2012-2015, 10 of 24 patients infected with matching genotypes of Mycobacterium tuberculosis received care at the same hospital in Gaborone, Botswana. Nosocomial transmission was initially suspected, but we discovered plausible sites of community transmission for 20 (95%) of 21 interviewed patients. Active case-finding at these sites could halt ongoing transmission.
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U2 - 10.3201/eid2303.161183
DO - 10.3201/eid2303.161183
M3 - Article
C2 - 27869604
AN - SCOPUS:85013328473
SN - 1080-6040
VL - 23
SP - 487
EP - 490
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 3
ER -