Mollusk-derived growth factor: Cloning and developmental expression in the central nervous system and reproductive tract of Aplysia

David Benjamin G. Akalal, Gregg Thomas Nagle

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

We have isolated and characterized an atrial gland cDNA that corrects the previously reported sequence for Aplysia atrial gland granule-specific antigen (AGSA), a glycoprotein of unknown function. We designated the protein mollusk-derived growth factor (MDGF) to distinguish the revised sequence from AGSA and to emphasize its similarity to an insect-derived growth factor (IDGF). We describe MDGF mRNA expression that suggests a possible role during embryonic development and CNS injury repair.

Original languageEnglish (US)
Pages (from-to)163-168
Number of pages6
JournalMolecular Brain Research
Volume91
Issue number1-2
DOIs
StatePublished - Jul 13 2001
Externally publishedYes

Fingerprint

Aplysia
Organism Cloning
Central Nervous System
Antigens
Embryonic Development
Insects
Intercellular Signaling Peptides and Proteins
Glycoproteins
Complementary DNA
Messenger RNA
Wounds and Injuries
Proteins
mollusk-derived growth factor

Keywords

  • Adenosine deaminase
  • Aplysia california
  • Glossina salivary gland growth factor-1 and 2
  • Human CECR1
  • Insect-derived growth factor
  • Male-specific IDGF
  • Mollusk-derived growth factor

ASJC Scopus subject areas

  • Molecular Biology
  • Cellular and Molecular Neuroscience

Cite this

Mollusk-derived growth factor : Cloning and developmental expression in the central nervous system and reproductive tract of Aplysia. / Akalal, David Benjamin G.; Nagle, Gregg Thomas.

In: Molecular Brain Research, Vol. 91, No. 1-2, 13.07.2001, p. 163-168.

Research output: Contribution to journalArticle

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