Mollusk-derived growth factor: Cloning and developmental expression in the central nervous system and reproductive tract of Aplysia

David Benjamin G. Akalal, Gregg Thomas Nagle

Research output: Contribution to journalArticle

17 Scopus citations


We have isolated and characterized an atrial gland cDNA that corrects the previously reported sequence for Aplysia atrial gland granule-specific antigen (AGSA), a glycoprotein of unknown function. We designated the protein mollusk-derived growth factor (MDGF) to distinguish the revised sequence from AGSA and to emphasize its similarity to an insect-derived growth factor (IDGF). We describe MDGF mRNA expression that suggests a possible role during embryonic development and CNS injury repair.

Original languageEnglish (US)
Pages (from-to)163-168
Number of pages6
JournalMolecular Brain Research
Issue number1-2
Publication statusPublished - Jul 13 2001
Externally publishedYes



  • Adenosine deaminase
  • Aplysia california
  • Glossina salivary gland growth factor-1 and 2
  • Human CECR1
  • Insect-derived growth factor
  • Male-specific IDGF
  • Mollusk-derived growth factor

ASJC Scopus subject areas

  • Molecular Biology
  • Cellular and Molecular Neuroscience

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