Mucinous adenocarcinomas of the vulva

Sharad A. Ghamande, John Kasznica, C. Thomas Griffiths, Neil J. Finkler, Adel M. Hamid

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

An 80-year-old nullipara had a 2.0-cm cystic tumor of the right labium majus. Histologic diagnosis was mucinous eccrine carcinoma. Seventy-five percent of these rare skin adnexal tumors arise on the face, eyelid, or scalp; but none has been reported on the vulva. Indolent localized growth is usual with regional nodal spread in 11% and distant metastases in 3%. A 67-year-old multi-para had a 1.2-cm polypoidal nodule of the posterior fourchette. Histologically, a colonic type mucinous carcinoma was arising within a villous adenoma. Mucicarmine and CEA stains were positive. Extensive workup failed to reveal other primary cancers in either patient. Both patients are well 19 and 17 months after radical vulvectomies and node-negative groin dissections. These cases illustrate further the diversity in cell type and biologic behavior of vulvar adenocarcinomas.

Original languageEnglish (US)
Pages (from-to)117-120
Number of pages4
JournalGynecologic Oncology
Volume57
Issue number1
DOIs
StatePublished - Apr 1995
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology

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    Ghamande, S. A., Kasznica, J., Griffiths, C. T., Finkler, N. J., & Hamid, A. M. (1995). Mucinous adenocarcinomas of the vulva. Gynecologic Oncology, 57(1), 117-120. https://doi.org/10.1006/gyno.1995.1108