Multiple sclerosis: When to suspect - Keys to diagnosis

David C Hess, Mary D. Hughes

Research output: Contribution to journalReview article

Abstract

Multiple sclerosis (MS) is characterized by a typical clinical history of neurologic symptoms, separated in time and space, supported by laboratory tests. Key symptoms that signal MS-particularly in young adults-include unilateral vision loss, diplopia that lasts for days or weeks, and hemiparesis that has an insidious or slow onset. A Lhermitte sign can often be elicited, although this finding is not specific for MS. An MRI scan typically shows high-signal lesions on T2-weighted images in the periventricular white matter and often in the cerebellum and brainstem. The presence of oligoclonal bands in the cerebrospinal fluid is a useful but not essential finding to support the diagnosis of MS.

Original languageEnglish (US)
Pages (from-to)844-852
Number of pages9
JournalConsultant
Volume45
Issue number8
StatePublished - Jul 1 2005

Fingerprint

Multiple Sclerosis
Oligoclonal Bands
Diplopia
Paresis
Neurologic Manifestations
Cerebellum
Brain Stem
Cerebrospinal Fluid
Young Adult
Magnetic Resonance Imaging

Keywords

  • Multiple sclerosis
  • Optic neuritis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Multiple sclerosis : When to suspect - Keys to diagnosis. / Hess, David C; Hughes, Mary D.

In: Consultant, Vol. 45, No. 8, 01.07.2005, p. 844-852.

Research output: Contribution to journalReview article

Hess, DC & Hughes, MD 2005, 'Multiple sclerosis: When to suspect - Keys to diagnosis', Consultant, vol. 45, no. 8, pp. 844-852.
Hess, David C ; Hughes, Mary D. / Multiple sclerosis : When to suspect - Keys to diagnosis. In: Consultant. 2005 ; Vol. 45, No. 8. pp. 844-852.
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