Multiple signalling modalities mediated by dendritic exocytosis of oxytocin and vasopressin

Mike Ludwig, Javier Stern

Research output: Contribution to journalArticle

23 Scopus citations


The mammalian hypothalamic magnocellular neurons of the supraoptic and paraventricular nuclei are among the best understood of all peptidergic neurons. Through their anatomical features, vasopressin- and oxytocincontaining neurons have revealed many important aspects of dendritic functions. Here, we review our understanding of the mechanisms of somato-dendritic peptide release, and the effects of autocrine, paracrine and hormone-like signalling on neuronal networks and behaviour.

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalPhilosophical Transactions of the Royal Society B: Biological Sciences
Issue number1672
StatePublished - Jul 5 2015



  • Calcium
  • Homeostasis
  • Hypothalamus
  • Paraventricular nucleus
  • Priming
  • Supraoptic nucleus

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this