Multiple signalling modalities mediated by dendritic exocytosis of oxytocin and vasopressin

Mike Ludwig, Javier Stern

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

The mammalian hypothalamic magnocellular neurons of the supraoptic and paraventricular nuclei are among the best understood of all peptidergic neurons. Through their anatomical features, vasopressin- and oxytocincontaining neurons have revealed many important aspects of dendritic functions. Here, we review our understanding of the mechanisms of somato-dendritic peptide release, and the effects of autocrine, paracrine and hormone-like signalling on neuronal networks and behaviour.

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalPhilosophical Transactions of the Royal Society B: Biological Sciences
Volume370
Issue number1672
DOIs
StatePublished - Jul 5 2015

Keywords

  • Calcium
  • Homeostasis
  • Hypothalamus
  • Paraventricular nucleus
  • Priming
  • Supraoptic nucleus

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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