TY - JOUR
T1 - Neurocognitive and behavioral profiles of children with Landau-Kleffner syndrome
AU - Riccio, Cynthia A.
AU - Vidrine, Stephanie M.
AU - Cohen, Morris J.
AU - Acosta-Cotte, Delmaris
AU - Park, Yong
N1 - Publisher Copyright:
© 2017 Taylor & Francis.
PY - 2017/10/2
Y1 - 2017/10/2
N2 - This is a retrospective study of 14 cases of children with Landau-Kleffner syndrome (LKS), the most prominent feature of which is acquired aphasia. These children were followed at a tertiary care pediatric epilepsy center. From the research data base, all LKS cases with neuropsychological evaluation were extracted. Children ranged in age from 6 to 13 years (M = 9.12; SD = 2.19) at the time of assessment (1 to 10 years post-onset). The majority of the children were white males, and all but one continued to experience seizure activity. Global intellectual functioning ranged from 59 to 101 (M = 82.07; SD = 12.14). Across the 14 cases reviewed, the neuropsychological profiles are considered in the context of neurological and syndrome-related factors. For these cases, 86% demonstrated continued expressive, and 50% had receptive language problems with 57% exhibiting poor auditory processing. Furthermore, 50 to 57% had deficits in auditory working memory and verbal memory. Academically, the majority had poor reading fluency and comprehension; 50% exhibited difficulty with mathematics. Finally, 57% evidenced attentional or other behavioral problems. Better understanding of LKS can assist in targeted assessment and intervention planning.
AB - This is a retrospective study of 14 cases of children with Landau-Kleffner syndrome (LKS), the most prominent feature of which is acquired aphasia. These children were followed at a tertiary care pediatric epilepsy center. From the research data base, all LKS cases with neuropsychological evaluation were extracted. Children ranged in age from 6 to 13 years (M = 9.12; SD = 2.19) at the time of assessment (1 to 10 years post-onset). The majority of the children were white males, and all but one continued to experience seizure activity. Global intellectual functioning ranged from 59 to 101 (M = 82.07; SD = 12.14). Across the 14 cases reviewed, the neuropsychological profiles are considered in the context of neurological and syndrome-related factors. For these cases, 86% demonstrated continued expressive, and 50% had receptive language problems with 57% exhibiting poor auditory processing. Furthermore, 50 to 57% had deficits in auditory working memory and verbal memory. Academically, the majority had poor reading fluency and comprehension; 50% exhibited difficulty with mathematics. Finally, 57% evidenced attentional or other behavioral problems. Better understanding of LKS can assist in targeted assessment and intervention planning.
KW - Aphasia
KW - Landau-Kleffner syndrome
KW - epilepsy
KW - inattention
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U2 - 10.1080/21622965.2016.1197127
DO - 10.1080/21622965.2016.1197127
M3 - Article
C2 - 27355396
AN - SCOPUS:84976347354
SN - 2162-2965
VL - 6
SP - 345
EP - 354
JO - Applied Neuropsychology: Child
JF - Applied Neuropsychology: Child
IS - 4
ER -