New antifungal agents

J. L. Lesher

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

This article, rather than presenting an overview of all available antifungal agents, has provided an update on new information about older agents, as well as evolving information about new agents, including those currently undergoing clinical trials. Among the azoles, ketoconazole will continue to be used as a major antifungal agent in dermatology, but one must keep up with its side effects and drug interactions. The place of the new triazole fluconazole in the treatment of cutaneous fungal infections needs to be clarified by additional controlled studies. Other agents on the horizon which are still undergoing investigation include itraconazole, which should be especially useful for dermatophyte (including tinea unguium) and candidal infections, sporotrichosis, and unusual infections such as aspergillosis and phaeohyphomycosis; and terbinafine, a member of the new class of antifungals called allylamines, which is an orally and topically active fungicidal agent that should be very useful for all types of dermatophyte infections. Research continues into the effectiveness of members of other classes of antifungals, including piritetrate, cilofungin, and amorolfine. In the 1990s, dermatologists should have safer, more effective antifungal agents for treating cutaneous fungal infections.

Original languageEnglish (US)
Pages (from-to)799-805
Number of pages7
JournalDermatologic Clinics
Volume10
Issue number4
StatePublished - Jan 1 1992

Fingerprint

Antifungal Agents
Arthrodermataceae
terbinafine
Mycoses
cilofungin
Phaeohyphomycosis
Infection
Allylamine
Sporotrichosis
Onychomycosis
Azoles
Skin
Triazoles
Ketoconazole
Itraconazole
Aspergillosis
Fluconazole
Dermatology
Drug-Related Side Effects and Adverse Reactions
Drug Interactions

ASJC Scopus subject areas

  • Dermatology

Cite this

Lesher, J. L. (1992). New antifungal agents. Dermatologic Clinics, 10(4), 799-805.

New antifungal agents. / Lesher, J. L.

In: Dermatologic Clinics, Vol. 10, No. 4, 01.01.1992, p. 799-805.

Research output: Contribution to journalReview article

Lesher, JL 1992, 'New antifungal agents', Dermatologic Clinics, vol. 10, no. 4, pp. 799-805.
Lesher JL. New antifungal agents. Dermatologic Clinics. 1992 Jan 1;10(4):799-805.
Lesher, J. L. / New antifungal agents. In: Dermatologic Clinics. 1992 ; Vol. 10, No. 4. pp. 799-805.
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