Noninferiority of antibody response to human papillomavirus type 16 in subjects vaccinated with monovalent and quadrivalent L1 virus-like particle vaccines

Suzanne M. Garland, Marc Steben, Mauricio Hernandez-Avila, Laura A. Koutsky, Cosette M. Wheeler, Gonzalo Perez, Diane M. Harper, Sepp Leodolter, Grace W.K. Tang, Daron Gale Ferris, Mark T. Esser, Scott C. Vuocolo, Micki Nelson, Radha Railkar, Carlos Sattler, Eliav Barr

Research output: Contribution to journalArticle

32 Scopus citations


The incorporation of multiple antigens into a single human papillomavirus (HPV) vaccine may induce immune interference. To evaluate whether interference occurs when HPV type 16 (HPV16) virus-like particles are combined in a multivalent vaccine, we conducted a study to evaluate anti-HPV16 responses among subjects receiving three-dose regimens of either a monovalent HPV16 vaccine or a quadrivalent HPV (types 6, 11, 16, and 18) vaccine.

Original languageEnglish (US)
Pages (from-to)792-795
Number of pages4
JournalClinical and Vaccine Immunology
Issue number6
Publication statusPublished - Jun 1 2007


ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Clinical Biochemistry
  • Microbiology (medical)

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