Novel mechanisms of endothelial dysfunction in diabetes

Research output: Contribution to journalArticle

63 Scopus citations

Abstract

Diabetes mellitus is a major risk factor for cardiovascular morbidity and mortality. This condition increases the risk of developing coronary, cerebrovascular, and peripheral arterial disease fourfold. Endothelial dysfunction is a major contributor to the pathogenesis of vascular disease in diabetes mellitus patients and has recently received increased attention. In this review article, some recent developments that could improve the knowledge of diabetes-induced endothelial dysfunction are discussed.

Original languageEnglish (US)
Pages (from-to)59-63
Number of pages5
JournalJournal of Cardiovascular Disease Research
Volume1
Issue number2
DOIs
StatePublished - 2010

Keywords

  • Arginase
  • diabetes
  • endothelial dysfunction
  • protein kinase C
  • reactive oxygen species
  • tumor necrosis factor

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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