Observation of the resting and pulsed states of cytochrome c oxidase in electrode-supported lipid bilayer membranes

James Burgess, Melissa C. Rhoten, Fred M. Hawkridge

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

Cytochrome c oxidase immobilized in lipid bilayer membranes on gold electrodes mediates electron transfer between reduced cytochrome c in solution and the electrode. Under flow conditions, fixed potential amperometry of anaerobic solutions of reduced cytochrome c shows changes in the rate of enzyme mediated electron transfer from cytochrome c to oxidase modified electrodes. These data are consistent with literature that describes both activation of the resting oxidase state to the pulsed oxidase state and subsequent decay of the pulsed oxidase state to the resting oxidase state.

Original languageEnglish (US)
Pages (from-to)4488-4491
Number of pages4
JournalJournal of the American Chemical Society
Volume120
Issue number18
DOIs
StatePublished - May 13 1998

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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