Opportunities for targeting the fatigue-anorexia-cachexia symptom cluster

Erin R. Alesi, Egidio Del Fabbro

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


Cancer patients experience multiple symptoms throughout their illness trajectory. Symptoms consistently occurring together, known as symptom clusters, share common pathophysiologic mechanisms. Understanding and targeting such symptom clusters may allow for more effective and efficient use of treatments for a variety of symptoms. Fatigue-anorexia-cachexia is one of the most prevalent symptom clusters and significantly impairs quality of life. In this review, we explore the fatigue-anorexia-cachexia symptom cluster and focus on current and emerging therapies with an emphasis on pharmacologic management.

Original languageEnglish (US)
Pages (from-to)325-329
Number of pages5
JournalCancer Journal
Issue number5
StatePublished - 2014
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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