Opsoclonus in Hemophilus influenzae meningitis

M. H. Rivner; W. M. Jay; J. B. Green; P. R. Dyken

doi:10.1212/wnl.32.6.661

Opsoclonus in Hemophilus influenzae meningitis

M. H. Rivner, W. M. Jay, J. B. Green, P. R. Dyken

Neurology

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21 Scopus citations

Abstract

We studied a 3-month-old boy who had opsoclonus in association with acute bacterial meningitis. The CSF IgG and IgM were elevated acutely, gradually returning to normal with clinical im provement. Correspondingly, CSF cytomorphology showed excessive plasmocytosis and a higher proportion of reactive lymphocytes than expected in an acute bacterial meningitis. These abnormalities in CSF cytology are effects of an abnormal immune response in the CNS, and provide evidence to support an immunopathic basis to opsoclonus.

Original language	English (US)
Pages (from-to)	661-663
Number of pages	3
Journal	Neurology
Volume	32
Issue number	6
DOIs	https://doi.org/10.1212/wnl.32.6.661
State	Published - Jun 1982

ASJC Scopus subject areas

Clinical Neurology

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AB - We studied a 3-month-old boy who had opsoclonus in association with acute bacterial meningitis. The CSF IgG and IgM were elevated acutely, gradually returning to normal with clinical im provement. Correspondingly, CSF cytomorphology showed excessive plasmocytosis and a higher proportion of reactive lymphocytes than expected in an acute bacterial meningitis. These abnormalities in CSF cytology are effects of an abnormal immune response in the CNS, and provide evidence to support an immunopathic basis to opsoclonus.

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