Optimizing potential for fertility: fertility considerations for the pediatrician.

Peter A. Lee, Alan Rogol, Christopher P. Houk

Research output: Contribution to journalArticle

Abstract

Whether for the prepubertal or pubertal child, the goal of fertility preservation is to obtain cells or tissues to be used to produce future children. For the prepubertal child, preservation efforts involve germ cells, earlier forms of sperm, and immature follicles, rather than mature spermatozoa or follicles. Options for prepubertal children include for boys freezing testicular tissue and extracting testicular sperm or for girls obtaining ovarian cortical or follicular tissue for storage. These procedures involve extraction and storage of immature gametes for subsequent in vitro maturation, although attempts for sperm currently involve only animal studies. For adolescent subjects who have sufficient gonadal development and reserve, sperm, oocytes, and ovarian cortex can be retrieved as among adults.

Original languageEnglish (US)
JournalPediatric Clinics of North America
Volume58
Issue number5
StatePublished - Oct 1 2011
Externally publishedYes

Fingerprint

Fertility
Spermatozoa
Germ Cells
Fertility Preservation
Freezing
Oocytes
Pediatricians

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Optimizing potential for fertility : fertility considerations for the pediatrician. / Lee, Peter A.; Rogol, Alan; Houk, Christopher P.

In: Pediatric Clinics of North America, Vol. 58, No. 5, 01.10.2011.

Research output: Contribution to journalArticle

@article{c9a6f356aece46aa94481d60243cda2d,
title = "Optimizing potential for fertility: fertility considerations for the pediatrician.",
abstract = "Whether for the prepubertal or pubertal child, the goal of fertility preservation is to obtain cells or tissues to be used to produce future children. For the prepubertal child, preservation efforts involve germ cells, earlier forms of sperm, and immature follicles, rather than mature spermatozoa or follicles. Options for prepubertal children include for boys freezing testicular tissue and extracting testicular sperm or for girls obtaining ovarian cortical or follicular tissue for storage. These procedures involve extraction and storage of immature gametes for subsequent in vitro maturation, although attempts for sperm currently involve only animal studies. For adolescent subjects who have sufficient gonadal development and reserve, sperm, oocytes, and ovarian cortex can be retrieved as among adults.",
author = "Lee, {Peter A.} and Alan Rogol and Houk, {Christopher P.}",
year = "2011",
month = "10",
day = "1",
language = "English (US)",
volume = "58",
journal = "Pediatric Clinics of North America",
issn = "0031-3955",
publisher = "W.B. Saunders Ltd",
number = "5",

}

TY - JOUR

T1 - Optimizing potential for fertility

T2 - fertility considerations for the pediatrician.

AU - Lee, Peter A.

AU - Rogol, Alan

AU - Houk, Christopher P.

PY - 2011/10/1

Y1 - 2011/10/1

N2 - Whether for the prepubertal or pubertal child, the goal of fertility preservation is to obtain cells or tissues to be used to produce future children. For the prepubertal child, preservation efforts involve germ cells, earlier forms of sperm, and immature follicles, rather than mature spermatozoa or follicles. Options for prepubertal children include for boys freezing testicular tissue and extracting testicular sperm or for girls obtaining ovarian cortical or follicular tissue for storage. These procedures involve extraction and storage of immature gametes for subsequent in vitro maturation, although attempts for sperm currently involve only animal studies. For adolescent subjects who have sufficient gonadal development and reserve, sperm, oocytes, and ovarian cortex can be retrieved as among adults.

AB - Whether for the prepubertal or pubertal child, the goal of fertility preservation is to obtain cells or tissues to be used to produce future children. For the prepubertal child, preservation efforts involve germ cells, earlier forms of sperm, and immature follicles, rather than mature spermatozoa or follicles. Options for prepubertal children include for boys freezing testicular tissue and extracting testicular sperm or for girls obtaining ovarian cortical or follicular tissue for storage. These procedures involve extraction and storage of immature gametes for subsequent in vitro maturation, although attempts for sperm currently involve only animal studies. For adolescent subjects who have sufficient gonadal development and reserve, sperm, oocytes, and ovarian cortex can be retrieved as among adults.

UR - http://www.scopus.com/inward/record.url?scp=84856397863&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84856397863&partnerID=8YFLogxK

M3 - Article

C2 - 21981956

VL - 58

JO - Pediatric Clinics of North America

JF - Pediatric Clinics of North America

SN - 0031-3955

IS - 5

ER -