Oral candidiasis following steroid therapy for oral lichen planus

D. R. Marable, L. M. Bowers, T. L. Stout, C. M. Stewart, K. M. Berg, V. Sankar, Scott S. DeRossi, J. R. Thoppay, M. T. Brennan

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Objectives: The purpose of this multicentre study was to determine the incidence of oral candidiasis in patients treated with topical steroids for oral lichen planus (OLP) and to determine whether the application of a concurrent antifungal therapy prevented the development of an oral candidiasis in these patients. Materials and Methods: Records of 315 patients with OLP seen at four Oral Medicine practices treated for at least 2 weeks with steroids with and without the use of an antifungal regimen were retrospectively reviewed. Results: The overall incidence of oral fungal infection in those treated with steroid therapy for OLP was 13.6%. There was no statistically significant difference in the rate of oral candidiasis development in those treated with an antifungal regimen vs those not treated prophylactically (14.3% vs 12.6%) (P = 0.68). Conclusions: Despite the use of various regimens, none of the preventive antifungal strategies used in this study resulted in a significant difference in the rate of development of an oral candidiasis in patients with OLP treated with steroids.

Original languageEnglish (US)
Pages (from-to)140-147
Number of pages8
JournalOral Diseases
Volume22
Issue number2
DOIs
StatePublished - Mar 1 2016

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Oral Lichen Planus
Oral Candidiasis
Steroids
Oral Medicine
Mycoses
Incidence
Therapeutics
Multicenter Studies

Keywords

  • Oral candidiasis
  • Oral lichen planus
  • Steroids

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Dentistry(all)

Cite this

Marable, D. R., Bowers, L. M., Stout, T. L., Stewart, C. M., Berg, K. M., Sankar, V., ... Brennan, M. T. (2016). Oral candidiasis following steroid therapy for oral lichen planus. Oral Diseases, 22(2), 140-147. https://doi.org/10.1111/odi.12399

Oral candidiasis following steroid therapy for oral lichen planus. / Marable, D. R.; Bowers, L. M.; Stout, T. L.; Stewart, C. M.; Berg, K. M.; Sankar, V.; DeRossi, Scott S.; Thoppay, J. R.; Brennan, M. T.

In: Oral Diseases, Vol. 22, No. 2, 01.03.2016, p. 140-147.

Research output: Contribution to journalArticle

Marable, DR, Bowers, LM, Stout, TL, Stewart, CM, Berg, KM, Sankar, V, DeRossi, SS, Thoppay, JR & Brennan, MT 2016, 'Oral candidiasis following steroid therapy for oral lichen planus', Oral Diseases, vol. 22, no. 2, pp. 140-147. https://doi.org/10.1111/odi.12399
Marable DR, Bowers LM, Stout TL, Stewart CM, Berg KM, Sankar V et al. Oral candidiasis following steroid therapy for oral lichen planus. Oral Diseases. 2016 Mar 1;22(2):140-147. https://doi.org/10.1111/odi.12399
Marable, D. R. ; Bowers, L. M. ; Stout, T. L. ; Stewart, C. M. ; Berg, K. M. ; Sankar, V. ; DeRossi, Scott S. ; Thoppay, J. R. ; Brennan, M. T. / Oral candidiasis following steroid therapy for oral lichen planus. In: Oral Diseases. 2016 ; Vol. 22, No. 2. pp. 140-147.
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