Oral Tissue Reactions to Suture Materials

Knut A. Selvig, Guy R. Biagiotti, Knut N. Leknes, Ulf M E Wikesjö

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Tissue reactions to natural and synthetic braided and monofilament suture materials in gingiva and oral mucosa were studied. A total of 138 sutures made of four commonly used materials were placed in the edentulous ridges and vestibular mucosa of eight beagle dogs. Biopsy specimens including the suture loop and surrounding tissues were obtained after 3, 7, and 14 days and processed for histologic analysis. The inflammatory reaction was more rapid and intense than the reaction that has been reported after suture placement in skin. Bacterial invasion of the suture track was a common sequela regardless of the material used, but it was particularly prominent for silk. The formation of a perisutural epithelial sleeve was well under way at 3 days and in some instances included the entire suture track within 7 days. Connective tissue reactions consisted of several well-defined, concentric perisutural zones. At 14 days, these zones were partly replaced by granulation tissue surrounded by a fibrous capsule. The synthetic monofilament suture elicited a mild inflammatory tissue response. The results showed that sutures placed in gingiva and oral mucosa produce a prolonged tissue response that is most likely a result of the continual influx of microbial contamination along the suture channel, which may be a lesser problem when sutures are placed in other surgical compartments. The results indicate that chromic gut sutures are rapidly and unpredictably absorbed when used in an environment characterized by moisture and infectious potential.

Original languageEnglish (US)
Pages (from-to)475-487
Number of pages13
JournalInternational Journal of Periodontics and Restorative Dentistry
Volume18
Issue number5
StatePublished - Jan 1 1998

Fingerprint

Sutures
Mouth Mucosa
Gingiva
Silk
Granulation Tissue
Connective Tissue
Capsules
Mucous Membrane
Dogs
Biopsy
Skin

ASJC Scopus subject areas

  • Oral Surgery
  • Periodontics

Cite this

Selvig, K. A., Biagiotti, G. R., Leknes, K. N., & Wikesjö, U. M. E. (1998). Oral Tissue Reactions to Suture Materials. International Journal of Periodontics and Restorative Dentistry, 18(5), 475-487.

Oral Tissue Reactions to Suture Materials. / Selvig, Knut A.; Biagiotti, Guy R.; Leknes, Knut N.; Wikesjö, Ulf M E.

In: International Journal of Periodontics and Restorative Dentistry, Vol. 18, No. 5, 01.01.1998, p. 475-487.

Research output: Contribution to journalArticle

Selvig, KA, Biagiotti, GR, Leknes, KN & Wikesjö, UME 1998, 'Oral Tissue Reactions to Suture Materials', International Journal of Periodontics and Restorative Dentistry, vol. 18, no. 5, pp. 475-487.
Selvig KA, Biagiotti GR, Leknes KN, Wikesjö UME. Oral Tissue Reactions to Suture Materials. International Journal of Periodontics and Restorative Dentistry. 1998 Jan 1;18(5):475-487.
Selvig, Knut A. ; Biagiotti, Guy R. ; Leknes, Knut N. ; Wikesjö, Ulf M E. / Oral Tissue Reactions to Suture Materials. In: International Journal of Periodontics and Restorative Dentistry. 1998 ; Vol. 18, No. 5. pp. 475-487.
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