Original Research: A case-control genome-wide association study identifies genetic modifiers of fetal hemoglobin in sickle cell disease

Medicine & Life Sciences

• Fetal Hemoglobin 100%
• Globins 94%
• Sickle Cell Anemia 82%
• Genome-Wide Association Study 78%
• Single Nucleotide Polymorphism 63%
• Linkage Disequilibrium 51%
• CREB-Binding Protein 43%
• Haplotypes 28%
• Genes 24%
• Chromosomes, Human, Pair 11 19%
• Erythroid Cells 18%
• Mutation 16%
• Response Elements 16%
• Blood Group Antigens 16%
• Codon 14%
• Introns 14%
• African Americans 14%
• Small Interfering RNA 12%
• Research Design 11%
• Binding Sites 11%
• Phenotype 9%
• Control Groups 8%
• Proteins 5%

Chemical Compounds

• Hemoglobin 69%
• Mutation 42%
• Globin 31%
• Protein 31%
• Enhancer 29%
• Disorder 21%
• Binding Site 17%