Yeasts belonging to the genus Torulopsis, though generally considered saprophytes, are capable of causing serious illness in compromised patients. Torulopsis infections in patients with no apparent underlying disease are rare. We have described a previously healthy man who had osteomyelitis due to Torulopsis holmii as a complication of a penetrating hand injury. Despite in vitro susceptibility of the organism to amphotericin B and flucytosine and prolonged therapy with these agents, the infection relapsed after an apparent initial response.
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