Ovulation and birth after administration of progesterone trigger—two case reports

Lina Villar; Beata Tralik; Michael P. Diamond; Michael Allon; Israel Maldonado; Dmitri I. Dozortsev

doi:10.1007/s10815-023-02750-x

Ovulation and birth after administration of progesterone trigger—two case reports

Lina Villar, Beata Tralik, Michael P. Diamond, Michael Allon, Israel Maldonado, Dmitri I. Dozortsev

Obstetrics and Gynecology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Purpose: To determine whether using progesterone as a trigger of a gonadotropin surge will induce ovulation and a competent corpus luteum. Methods: Patients were administered 5 or 10 mg of progesterone intramuscularly when the leading follicle reached preovulatory size. Results: We demonstrate that progesterone injections result in classical ultrasonographic hallmarks of ovulation about 48 h later and the formation of a corpus luteum competent to support pregnancy. Conclusion: Our results support further exploration of using progesterone to trigger a gonadotropin surge in assisted human reproduction.

Original language	English (US)
Pages (from-to)	1037-1044
Number of pages	8
Journal	Journal of Assisted Reproduction and Genetics
Volume	40
Issue number	5
DOIs	https://doi.org/10.1007/s10815-023-02750-x
State	Published - May 2023

Keywords

IUI
IVF
Ovulation
Pregnancy
Progesterone
Timed intercourse
Trigger
surge

ASJC Scopus subject areas

Reproductive Medicine
Genetics
Obstetrics and Gynecology
Developmental Biology
Genetics(clinical)

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10.1007/s10815-023-02750-x

Cite this

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abstract = "Purpose: To determine whether using progesterone as a trigger of a gonadotropin surge will induce ovulation and a competent corpus luteum. Methods: Patients were administered 5 or 10 mg of progesterone intramuscularly when the leading follicle reached preovulatory size. Results: We demonstrate that progesterone injections result in classical ultrasonographic hallmarks of ovulation about 48 h later and the formation of a corpus luteum competent to support pregnancy. Conclusion: Our results support further exploration of using progesterone to trigger a gonadotropin surge in assisted human reproduction.",

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AU - Tralik, Beata

AU - Diamond, Michael P.

AU - Allon, Michael

AU - Maldonado, Israel

AU - Dozortsev, Dmitri I.

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Ovulation and birth after administration of progesterone trigger—two case reports

Abstract

Keywords

ASJC Scopus subject areas

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