Oxidative ring opening of 2,5-diarylfurans by Selectfluor®

Stephen J. Blank, Chad E. Stephens

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Attempted fluorination of some 2,5-diarylfurans with the N-F reagent Selectfluor® has led instead to oxidative ring opening of the furan ring to give the cis-enedione, along with traces of the trans isomer, in good isolated yield.

Original languageEnglish (US)
Pages (from-to)6849-6850
Number of pages2
JournalTetrahedron Letters
Volume47
Issue number38
DOIs
StatePublished - Sep 18 2006
Externally publishedYes

Keywords

  • Fluorination
  • Furan
  • Oxidative ring opening
  • Selectfluor
  • cis-Enedione

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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