P1 (adenosine) purinoceptor assays

S. Jamal Mustafa, Habib R. Ansari, Worku Abebe

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

P1 purinoceptors, or adenosine (ADO) receptors, mediate the biological effects of the endogenous nucleoside, ADO and its analogs. ADO works through four receptor subtypes: A 1, A 2A, A 2B, and A 3. Isolated tissue assays used for the pharmacological characterization of ADO receptors based on functional responses are described in this unit. The guinea pig atrium, pig coronary artery, guinea pig aorta, and mouse aorta have been used for the characterization of ADO receptor subtypes.

Original languageEnglish (US)
Pages (from-to)4.7.1-4.7.13
JournalCurrent protocols in pharmacology
Issue numberSUPPL. 45
DOIs
StatePublished - Jun 16 2009

Keywords

  • Adenosine receptors
  • Guinea pig aorta
  • Guinea pig atrium
  • Isolated tissues
  • Mouse aorta
  • P1 purinoceptors
  • Pig coronary artery

ASJC Scopus subject areas

  • Pharmacology

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