A versatile class of 2-aminopyrroles containing various electron-withdrawing substituents at the 3-position have been N-arylated on the amine using a palladiumcatalyzed cross-coupling reaction. Using this methodology, a pyrimidone-based tricyclic system has been prepared in just one step from a starting 2-aminopyrrole.
- Pyrrolo[2,3-d] pyrido[1,2-a]pyrimidine
ASJC Scopus subject areas
- Organic Chemistry