Purpose: Because of the dismal outcomes of conventional therapies for pancreatic carcinomas, we postulated that hypoxia may exist within these tumors. Methods and Materials: Seven sequential patients with adenocarcinomas of the pancreas consented to intraoperative measurements of tumor oxygenation using the Eppendorf (Hamburg, Germany) polargraphic electrode. Results: All 7 tumors demonstrated significant tumor hypoxia. In contrast, adjacent normal pancreas showed normal oxygenation. Conclusion: Tumor hypoxia exists within pancreatic cancers. Copyright (C) 2000 Elsevier Science Inc.
|Original language||English (US)|
|Number of pages||4|
|Journal||International Journal of Radiation Oncology Biology Physics|
|State||Published - Nov 1 2000|
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Cancer Research