Paraneoplastic autoimmune multiorgan syndrome (paraneoplastic pemphigus) in a child: Case report and review of the literature

Joshua E. Lane, Carol Woody, Loretta S. Davis, Margaret F. Guill, Rita S. Jerath

Research output: Contribution to journalReview article

28 Scopus citations

Abstract

Paraneoplastic autoimmune multiorgan syndrome, also known as paraneoplastic pemphigus, has been observed only rarely among children. We describe a 10-year-old boy with typical clinical and histologic findings of paraneoplastic pemphigus associated with Castleman's disease. His disease was refractory to resection of the tumor and aggressive combination immunosuppressive therapies. The patient died 1 year after presentation, as a result of complications of bronchiolitis obliterans. This case is unusual because of the young age of the patient.

Original languageEnglish (US)
Pages (from-to)e513-e516
JournalPediatrics
Volume114
Issue number4
DOIs
StatePublished - Oct 1 2004

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Keywords

  • Castleman's tumor
  • Child
  • Paraneoplastic autoimmune multiorgan syndrome
  • Paraneoplastic pemphigus

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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