Paraneoplastic autoimmune multiorgan syndrome (paraneoplastic pemphigus) in a child

Case report and review of the literature

Joshua E. Lane, Carol Woody, Loretta S Davis, Margaret Frank Guill, Rita S Jerath

Research output: Contribution to journalReview article

26 Citations (Scopus)

Abstract

Paraneoplastic autoimmune multiorgan syndrome, also known as paraneoplastic pemphigus, has been observed only rarely among children. We describe a 10-year-old boy with typical clinical and histologic findings of paraneoplastic pemphigus associated with Castleman's disease. His disease was refractory to resection of the tumor and aggressive combination immunosuppressive therapies. The patient died 1 year after presentation, as a result of complications of bronchiolitis obliterans. This case is unusual because of the young age of the patient.

Original languageEnglish (US)
JournalPediatrics
Volume114
Issue number4
DOIs
StatePublished - Oct 1 2004

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Paraneoplastic Syndromes
Pemphigus
Bronchiolitis Obliterans
Giant Lymph Node Hyperplasia
Immunosuppressive Agents
Neoplasms
Therapeutics

Keywords

  • Castleman's tumor
  • Child
  • Paraneoplastic autoimmune multiorgan syndrome
  • Paraneoplastic pemphigus

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Paraneoplastic autoimmune multiorgan syndrome (paraneoplastic pemphigus) in a child : Case report and review of the literature. / Lane, Joshua E.; Woody, Carol; Davis, Loretta S; Guill, Margaret Frank; Jerath, Rita S.

In: Pediatrics, Vol. 114, No. 4, 01.10.2004.

Research output: Contribution to journalReview article

Lane, Joshua E. ; Woody, Carol ; Davis, Loretta S ; Guill, Margaret Frank ; Jerath, Rita S. / Paraneoplastic autoimmune multiorgan syndrome (paraneoplastic pemphigus) in a child : Case report and review of the literature. In: Pediatrics. 2004 ; Vol. 114, No. 4.
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