Parenteral Antibiotics and Carbohydrate Intolerance in Term Neonates

Jatinder J Bhatia, Alton R. Prihoda, C. Joan Richardson

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

To evaluate the effects of parenteral antibiotics on carbohydrate tolerance, fecal reducing substances, stool frequency, and dietary manipulation were monitored in two groups of term neonates. The first group consisted of neonates receiving parenteral ampicillin sodium and gentamicin sulfate. A second group (n=25) of matched neonates not receiving antibiotics served as controls. Most of the neonates were fed a standard lactose-containing formula and the remainder were breast-fed. Stool frequency, presence of fecal reducing substances, and requirement for dietary manipulation were significantly greater in neonates receiving antibiotics compared with controls. Infants manifesting symptomatic carbohydrate intolerance while receiving parenteral antibiotics may benefit either from receiving lactose-free formula or from decreasing the intake of lactose for the duration of antibiotic therapy.

Original languageEnglish (US)
Pages (from-to)111-113
Number of pages3
JournalAmerican Journal of Diseases of Children
Volume140
Issue number2
DOIs
StatePublished - Jan 1 1986
Externally publishedYes

Fingerprint

Newborn Infant
Anti-Bacterial Agents
Lactose
Nutritional Requirements
Ampicillin
Gentamicins
Breast
Carbohydrates
Glucose-Galactose Malabsorption
Therapeutics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Parenteral Antibiotics and Carbohydrate Intolerance in Term Neonates. / Bhatia, Jatinder J; Prihoda, Alton R.; Richardson, C. Joan.

In: American Journal of Diseases of Children, Vol. 140, No. 2, 01.01.1986, p. 111-113.

Research output: Contribution to journalArticle

Bhatia, Jatinder J ; Prihoda, Alton R. ; Richardson, C. Joan. / Parenteral Antibiotics and Carbohydrate Intolerance in Term Neonates. In: American Journal of Diseases of Children. 1986 ; Vol. 140, No. 2. pp. 111-113.
@article{412d9d41d5b54632b308cc03999992a5,
title = "Parenteral Antibiotics and Carbohydrate Intolerance in Term Neonates",
abstract = "To evaluate the effects of parenteral antibiotics on carbohydrate tolerance, fecal reducing substances, stool frequency, and dietary manipulation were monitored in two groups of term neonates. The first group consisted of neonates receiving parenteral ampicillin sodium and gentamicin sulfate. A second group (n=25) of matched neonates not receiving antibiotics served as controls. Most of the neonates were fed a standard lactose-containing formula and the remainder were breast-fed. Stool frequency, presence of fecal reducing substances, and requirement for dietary manipulation were significantly greater in neonates receiving antibiotics compared with controls. Infants manifesting symptomatic carbohydrate intolerance while receiving parenteral antibiotics may benefit either from receiving lactose-free formula or from decreasing the intake of lactose for the duration of antibiotic therapy.",
author = "Bhatia, {Jatinder J} and Prihoda, {Alton R.} and Richardson, {C. Joan}",
year = "1986",
month = "1",
day = "1",
doi = "10.1001/archpedi.1986.02140160029022",
language = "English (US)",
volume = "140",
pages = "111--113",
journal = "JAMA Pediatrics",
issn = "2168-6203",
publisher = "American Medical Association",
number = "2",

}

TY - JOUR

T1 - Parenteral Antibiotics and Carbohydrate Intolerance in Term Neonates

AU - Bhatia, Jatinder J

AU - Prihoda, Alton R.

AU - Richardson, C. Joan

PY - 1986/1/1

Y1 - 1986/1/1

N2 - To evaluate the effects of parenteral antibiotics on carbohydrate tolerance, fecal reducing substances, stool frequency, and dietary manipulation were monitored in two groups of term neonates. The first group consisted of neonates receiving parenteral ampicillin sodium and gentamicin sulfate. A second group (n=25) of matched neonates not receiving antibiotics served as controls. Most of the neonates were fed a standard lactose-containing formula and the remainder were breast-fed. Stool frequency, presence of fecal reducing substances, and requirement for dietary manipulation were significantly greater in neonates receiving antibiotics compared with controls. Infants manifesting symptomatic carbohydrate intolerance while receiving parenteral antibiotics may benefit either from receiving lactose-free formula or from decreasing the intake of lactose for the duration of antibiotic therapy.

AB - To evaluate the effects of parenteral antibiotics on carbohydrate tolerance, fecal reducing substances, stool frequency, and dietary manipulation were monitored in two groups of term neonates. The first group consisted of neonates receiving parenteral ampicillin sodium and gentamicin sulfate. A second group (n=25) of matched neonates not receiving antibiotics served as controls. Most of the neonates were fed a standard lactose-containing formula and the remainder were breast-fed. Stool frequency, presence of fecal reducing substances, and requirement for dietary manipulation were significantly greater in neonates receiving antibiotics compared with controls. Infants manifesting symptomatic carbohydrate intolerance while receiving parenteral antibiotics may benefit either from receiving lactose-free formula or from decreasing the intake of lactose for the duration of antibiotic therapy.

UR - http://www.scopus.com/inward/record.url?scp=0022637481&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022637481&partnerID=8YFLogxK

U2 - 10.1001/archpedi.1986.02140160029022

DO - 10.1001/archpedi.1986.02140160029022

M3 - Article

VL - 140

SP - 111

EP - 113

JO - JAMA Pediatrics

JF - JAMA Pediatrics

SN - 2168-6203

IS - 2

ER -