Abstract
Little information is available regarding the in-vivo effects of amphotericin B on organs other than the kidney. The increasing use of intrathecal amphotericin B has resulted in several reports of neurotoxicity associated with the drug. Development of parkinsonism following intraventricular treatment with amphotericin B for cryptococcal meningitis in a young woman suggested a direct toxic effect on nervous tissue by amphotericin B. Although transient signs of parkinsonism have been described in a patient receiving intraventricular amphotericin B, persistent parkinsonism is an unprecedented occurrence.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 97-99 |
| Number of pages | 3 |
| Journal | Journal of Antimicrobial Chemotherapy |
| Volume | 12 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 1983 |
ASJC Scopus subject areas
- Pharmacology
- Microbiology (medical)
- Infectious Diseases
- Pharmacology (medical)
