Parkinsonism associated with intraventricular amphotericin b

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Little information is available regarding the in-vivo effects of amphotericin B on organs other than the kidney. The increasing use of intrathecal amphotericin B has resulted in several reports of neurotoxicity associated with the drug. Development of parkinsonism following intraventricular treatment with amphotericin B for cryptococcal meningitis in a young woman suggested a direct toxic effect on nervous tissue by amphotericin B. Although transient signs of parkinsonism have been described in a patient receiving intraventricular amphotericin B, persistent parkinsonism is an unprecedented occurrence.

Original languageEnglish (US)
Pages (from-to)97-99
Number of pages3
JournalJournal of Antimicrobial Chemotherapy
Volume12
Issue number1
DOIs
StatePublished - Jul 1 1983

Fingerprint

Parkinsonian Disorders
Amphotericin B
Cryptococcal Meningitis
Nerve Tissue
Poisons
Kidney
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Pharmacology
  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Parkinsonism associated with intraventricular amphotericin b. / Fisher, John Fremont; Dewald, Jon.

In: Journal of Antimicrobial Chemotherapy, Vol. 12, No. 1, 01.07.1983, p. 97-99.

Research output: Contribution to journalArticle

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