Passive transfer of hepatitis antibodies during intravenous administration of immune globulin

P. Karna; D. L. Murray; D. Valduss; N. Mattarella; J. W. Dyke; G. A. Maier

doi:10.1016/S0022-3476(05)83296-2

Passive transfer of hepatitis antibodies during intravenous administration of immune globulin

P. Karna, D. L. Murray, D. Valduss, N. Mattarella, J. W. Dyke, G. A. Maier

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

We studied the effect of intravenous immune globulin (IVIG) infusion on the levels of hepatitis B and C antibodies in 10 premature babies. All four tested lots of a commercially purchased IVIG preparation were found to contain substantial amounts of hepatitis B core and hepatitis C antibodies. Our results show that passive transfer of hepatitis B and C virus antibodies occurred after IVIG infusion, and that the levels were dependent on the quantity of IVIG given. When assessing neonates for hepatitis, the factor of receipt of blood products, including IVIG, needs to be considered to interpret laboratory results.

Original language	English (US)
Pages (from-to)	463-465
Number of pages	3
Journal	The Journal of Pediatrics
Volume	125
Issue number	3
DOIs	https://doi.org/10.1016/S0022-3476(05)83296-2
State	Published - Sep 1994
Externally published	Yes

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0022-3476(05)83296-2

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abstract = "We studied the effect of intravenous immune globulin (IVIG) infusion on the levels of hepatitis B and C antibodies in 10 premature babies. All four tested lots of a commercially purchased IVIG preparation were found to contain substantial amounts of hepatitis B core and hepatitis C antibodies. Our results show that passive transfer of hepatitis B and C virus antibodies occurred after IVIG infusion, and that the levels were dependent on the quantity of IVIG given. When assessing neonates for hepatitis, the factor of receipt of blood products, including IVIG, needs to be considered to interpret laboratory results.",

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AU - Karna, P.

AU - Murray, D. L.

AU - Valduss, D.

AU - Mattarella, N.

AU - Dyke, J. W.

AU - Maier, G. A.

PY - 1994/9

Y1 - 1994/9

N2 - We studied the effect of intravenous immune globulin (IVIG) infusion on the levels of hepatitis B and C antibodies in 10 premature babies. All four tested lots of a commercially purchased IVIG preparation were found to contain substantial amounts of hepatitis B core and hepatitis C antibodies. Our results show that passive transfer of hepatitis B and C virus antibodies occurred after IVIG infusion, and that the levels were dependent on the quantity of IVIG given. When assessing neonates for hepatitis, the factor of receipt of blood products, including IVIG, needs to be considered to interpret laboratory results.

AB - We studied the effect of intravenous immune globulin (IVIG) infusion on the levels of hepatitis B and C antibodies in 10 premature babies. All four tested lots of a commercially purchased IVIG preparation were found to contain substantial amounts of hepatitis B core and hepatitis C antibodies. Our results show that passive transfer of hepatitis B and C virus antibodies occurred after IVIG infusion, and that the levels were dependent on the quantity of IVIG given. When assessing neonates for hepatitis, the factor of receipt of blood products, including IVIG, needs to be considered to interpret laboratory results.

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JO - The Journal of Pediatrics

JF - The Journal of Pediatrics

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ER -

Passive transfer of hepatitis antibodies during intravenous administration of immune globulin

Abstract

ASJC Scopus subject areas

UN SDGs

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