Pediatric recipients of adult laparoscopic donor nephrectomy

A single-institution outcome analysis

Zachary Klaassen, Prakash R. Paragi, H. Stephen Fletcher, Ronald S. Chamberlain, Stuart Geffner

Research output: Contribution to journalArticle

Abstract

Introduction: For more than a decade, adult laparoscopic donor nephrectomy (LDN) has been offered as a minimally invasive organ procurement modality for pediatric patients with end-stage renal disease. There is a paucity of literature reflecting pediatric recipient outcomes of adult LDN kidneys, and the objective of this study was to evaluate our institutional experience. Methods: Thirty-six pediatric patients were identified as recipients of adult LDN from 2000 to 2009 at our institution. results: The most common renal disease was dysplasia (N = 6) for those 0 to 5 years of age and nephronophthisis (N = 7) for those 6 to 18 years if age. The mean operative time for those 0 to 5 years of age was 262 ± 38 min and 216 ± 69 min for those 6 to 18 years (P < 0.04). Perioperative complications were more common in those 0 to 5 years of age (73 vs 24%, P < 0.01) and the length of stay (19.3 ± 20.8 days vs 4.8 ± 2.7 days, P < 0.001) was longer compared with those 6 to 18 years. conclusion: Pediatric recipients of adult LDN kidneys present unique surgical and hemodynamic challenges. Although renal transplants in pediatric patients are associated with postoperative morbidity, graft survival is comparable to adult LDN recipients.

Original languageEnglish (US)
JournalUroToday International Journal
Volume6
Issue number1
DOIs
StatePublished - Feb 1 2013
Externally publishedYes

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Nephrectomy
Tissue Donors
Pediatrics
Kidney
Tissue and Organ Procurement
Graft Survival
Operative Time
Chronic Kidney Failure
Length of Stay
Hemodynamics
Morbidity
Transplants

Keywords

  • Adult kidney donor
  • Laparoscopic donor nephrectomy
  • Outcomes
  • Pediatric

ASJC Scopus subject areas

  • Urology

Cite this

Pediatric recipients of adult laparoscopic donor nephrectomy : A single-institution outcome analysis. / Klaassen, Zachary; Paragi, Prakash R.; Fletcher, H. Stephen; Chamberlain, Ronald S.; Geffner, Stuart.

In: UroToday International Journal, Vol. 6, No. 1, 01.02.2013.

Research output: Contribution to journalArticle

Klaassen, Zachary ; Paragi, Prakash R. ; Fletcher, H. Stephen ; Chamberlain, Ronald S. ; Geffner, Stuart. / Pediatric recipients of adult laparoscopic donor nephrectomy : A single-institution outcome analysis. In: UroToday International Journal. 2013 ; Vol. 6, No. 1.
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