Percent weight reduction required to achieve minimal clinically important improvements in health-related quality of life among African Americans: A secondary analysis of the fit body and soul study

Barbara Jane Threatt Garvin, Lovoria B. Williams, Thomas Vayalinkara Joshua, Stephen Warwick Looney, Lucy Nelle Marion

Research output: Contribution to journalArticle

Abstract

Objective To calculate the percent weight reduction required to achieve minimal clinically important improvement (MCII) in health-related quality of life (HRQOL). Design Secondary data analysis from the longitudinal cohort of a single-blinded, cluster-randomized community trial to test the efficacy of the faith-based adaptation of the Diabetes Prevention Program. Setting African-American churches. Participants This study included 472 congregants with a body mass index of ≥ 25 and fasting plasma glucose < 126 mg/dl. Main outcome measure Percent weight reduction required to achieve the MCII in HRQOL measured by two instruments, SF-12 and EQ-5D, one year following baseline. Analysis The percent weight reduction required to achieve established MCII in SF-12 Physical Component Summary (PCS), SF-12 Mental Component Summary (MCS), and EQ-5D Health Status (HS) at one-year follow-up were calculated using fitted linear regression models. In addition to models for the total sample, we generated models, stratified by baseline BMI, PCS, and HS, to calculate the percent weight reduction required to achieve MCII in HRQOL for those most in need of weight reduction and those in need of improved HRQOL. Results The percent weight reduction was a significant predictor of improvement in the SF-12PCS and the EQ-5DHS but not SF-12MCS. To achieve a MCII in SF-12PCS and EQ-5DHS, 18% and 30% weight reductions were required, respectively. A smaller percent weight reduction was required when the baseline BMI was ≥ 40. Conclusions and implications Improvements in HRQOL among African-American congregants seeking weight reduction required more than the 3–5% weight reduction associated with improvements in physical health.

Original languageEnglish (US)
Pages (from-to)100-105
Number of pages6
JournalApplied Nursing Research
Volume36
DOIs
StatePublished - Aug 1 2017

Fingerprint

African Americans
Weight Loss
Quality of Life
Health Status
Linear Models
Fasting
Body Mass Index
Outcome Assessment (Health Care)
Glucose
Health

Keywords

  • African American
  • Body composition
  • Body mass index
  • EQ-5D
  • Health-related quality of life
  • Minimal clinically important difference
  • Obesity
  • Quality of life
  • SF-12
  • Waist circumference
  • Waist-to-height ratio

ASJC Scopus subject areas

  • Nursing(all)

Cite this

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title = "Percent weight reduction required to achieve minimal clinically important improvements in health-related quality of life among African Americans: A secondary analysis of the fit body and soul study",
abstract = "Objective To calculate the percent weight reduction required to achieve minimal clinically important improvement (MCII) in health-related quality of life (HRQOL). Design Secondary data analysis from the longitudinal cohort of a single-blinded, cluster-randomized community trial to test the efficacy of the faith-based adaptation of the Diabetes Prevention Program. Setting African-American churches. Participants This study included 472 congregants with a body mass index of ≥ 25 and fasting plasma glucose < 126 mg/dl. Main outcome measure Percent weight reduction required to achieve the MCII in HRQOL measured by two instruments, SF-12 and EQ-5D, one year following baseline. Analysis The percent weight reduction required to achieve established MCII in SF-12 Physical Component Summary (PCS), SF-12 Mental Component Summary (MCS), and EQ-5D Health Status (HS) at one-year follow-up were calculated using fitted linear regression models. In addition to models for the total sample, we generated models, stratified by baseline BMI, PCS, and HS, to calculate the percent weight reduction required to achieve MCII in HRQOL for those most in need of weight reduction and those in need of improved HRQOL. Results The percent weight reduction was a significant predictor of improvement in the SF-12PCS and the EQ-5DHS but not SF-12MCS. To achieve a MCII in SF-12PCS and EQ-5DHS, 18{\%} and 30{\%} weight reductions were required, respectively. A smaller percent weight reduction was required when the baseline BMI was ≥ 40. Conclusions and implications Improvements in HRQOL among African-American congregants seeking weight reduction required more than the 3–5{\%} weight reduction associated with improvements in physical health.",
keywords = "African American, Body composition, Body mass index, EQ-5D, Health-related quality of life, Minimal clinically important difference, Obesity, Quality of life, SF-12, Waist circumference, Waist-to-height ratio",
author = "Garvin, {Barbara Jane Threatt} and Williams, {Lovoria B.} and Joshua, {Thomas Vayalinkara} and Looney, {Stephen Warwick} and Marion, {Lucy Nelle}",
year = "2017",
month = "8",
day = "1",
doi = "10.1016/j.apnr.2017.06.002",
language = "English (US)",
volume = "36",
pages = "100--105",
journal = "Applied Nursing Research",
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T1 - Percent weight reduction required to achieve minimal clinically important improvements in health-related quality of life among African Americans

T2 - A secondary analysis of the fit body and soul study

AU - Garvin, Barbara Jane Threatt

AU - Williams, Lovoria B.

AU - Joshua, Thomas Vayalinkara

AU - Looney, Stephen Warwick

AU - Marion, Lucy Nelle

PY - 2017/8/1

Y1 - 2017/8/1

N2 - Objective To calculate the percent weight reduction required to achieve minimal clinically important improvement (MCII) in health-related quality of life (HRQOL). Design Secondary data analysis from the longitudinal cohort of a single-blinded, cluster-randomized community trial to test the efficacy of the faith-based adaptation of the Diabetes Prevention Program. Setting African-American churches. Participants This study included 472 congregants with a body mass index of ≥ 25 and fasting plasma glucose < 126 mg/dl. Main outcome measure Percent weight reduction required to achieve the MCII in HRQOL measured by two instruments, SF-12 and EQ-5D, one year following baseline. Analysis The percent weight reduction required to achieve established MCII in SF-12 Physical Component Summary (PCS), SF-12 Mental Component Summary (MCS), and EQ-5D Health Status (HS) at one-year follow-up were calculated using fitted linear regression models. In addition to models for the total sample, we generated models, stratified by baseline BMI, PCS, and HS, to calculate the percent weight reduction required to achieve MCII in HRQOL for those most in need of weight reduction and those in need of improved HRQOL. Results The percent weight reduction was a significant predictor of improvement in the SF-12PCS and the EQ-5DHS but not SF-12MCS. To achieve a MCII in SF-12PCS and EQ-5DHS, 18% and 30% weight reductions were required, respectively. A smaller percent weight reduction was required when the baseline BMI was ≥ 40. Conclusions and implications Improvements in HRQOL among African-American congregants seeking weight reduction required more than the 3–5% weight reduction associated with improvements in physical health.

AB - Objective To calculate the percent weight reduction required to achieve minimal clinically important improvement (MCII) in health-related quality of life (HRQOL). Design Secondary data analysis from the longitudinal cohort of a single-blinded, cluster-randomized community trial to test the efficacy of the faith-based adaptation of the Diabetes Prevention Program. Setting African-American churches. Participants This study included 472 congregants with a body mass index of ≥ 25 and fasting plasma glucose < 126 mg/dl. Main outcome measure Percent weight reduction required to achieve the MCII in HRQOL measured by two instruments, SF-12 and EQ-5D, one year following baseline. Analysis The percent weight reduction required to achieve established MCII in SF-12 Physical Component Summary (PCS), SF-12 Mental Component Summary (MCS), and EQ-5D Health Status (HS) at one-year follow-up were calculated using fitted linear regression models. In addition to models for the total sample, we generated models, stratified by baseline BMI, PCS, and HS, to calculate the percent weight reduction required to achieve MCII in HRQOL for those most in need of weight reduction and those in need of improved HRQOL. Results The percent weight reduction was a significant predictor of improvement in the SF-12PCS and the EQ-5DHS but not SF-12MCS. To achieve a MCII in SF-12PCS and EQ-5DHS, 18% and 30% weight reductions were required, respectively. A smaller percent weight reduction was required when the baseline BMI was ≥ 40. Conclusions and implications Improvements in HRQOL among African-American congregants seeking weight reduction required more than the 3–5% weight reduction associated with improvements in physical health.

KW - African American

KW - Body composition

KW - Body mass index

KW - EQ-5D

KW - Health-related quality of life

KW - Minimal clinically important difference

KW - Obesity

KW - Quality of life

KW - SF-12

KW - Waist circumference

KW - Waist-to-height ratio

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