Periodontal repair in dogs Healing patterns in large circumferential periodontal defects

U. M E Wikesjo, R. Nilveus

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

Abstract This report describes the healing patterns of large circumferential periodontal defects in the beagle dog. Approximately 5 mm large periodontal defects were created around the mandibular premolars (P2, P3 and P4) in 13 animals. The root surfaces were then instrumented to remove all cementum and the wounds immediately closed by replacing and suturing the flaps just coronal to the cemento‐enamel junction. Block biopsies were harvested after 4 weeks. Most of the surgically denuded root surface healed with connective tissue repair. Cementum formation and regeneration of alveolar bone was limited and averaged approximately 30% and 20%, respectively, of the defect height. Almost all teeth exhibited root resorption. Ankylosis was observed in 1/3 of the teeth. There was no difference in the healing response between the 3 premolars or their buccal and lingual surfaces. The range of healing responses indicates that a biological potential exists which makes this model useful for testing the effect of various root and wound conditioners in (1) enhancing cementum formation on the root surface, (2) increasing regeneration of alveolar bone and (3) preventing aberrant healing events such as root resorption and ankylosis. Conversely, whether such agents may compromise wound healing and result in reduced connective tissue repair may concomitantly be tested.

Original languageEnglish (US)
Pages (from-to)49-59
Number of pages11
JournalJournal of Clinical Periodontology
Volume18
Issue number1
DOIs
StatePublished - Jan 1 1991

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Dental Cementum
Root Resorption
Ankylosis
Bone Regeneration
Bicuspid
Dogs
Connective Tissue
Tooth Cervix
Tooth Root
Cheek
Wounds and Injuries
Tongue
Wound Healing
Tooth
Biopsy

Keywords

  • ankylosis
  • new attachment
  • periodontal regeneration
  • root resorption

ASJC Scopus subject areas

  • Periodontics

Cite this

Periodontal repair in dogs Healing patterns in large circumferential periodontal defects. / Wikesjo, U. M E; Nilveus, R.

In: Journal of Clinical Periodontology, Vol. 18, No. 1, 01.01.1991, p. 49-59.

Research output: Contribution to journalArticle

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