Periodontitis and breast cancer

A case-control study

Camila S. Sfreddo, Juliana Maier, Silvia C. De David, Cristiano Susin, Carlos Heitor C. Moreira

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Objectives: The aim of this case-control study was to evaluate the association between periodontitis and breast cancer in a sample of adult Brazilian women. Methods: This was a hospital-based study, which included 67 cases and 134 controls (1:2). Women were selected consecutively between April, 2013 and June, 2015 among those attending the Department of Gynecology at the University Hospital of Santa Maria. Cases were selected among women diagnosed with breast cancer (ICD-10 C50), and controls were matched for age (±2 years), and smoking status (never, former and current smoker). Conditional logistic regression was used to model the association between periodontitis and breast cancer with and without adjustment for potential confounders. Four case definitions for periodontitis were used. Results: Cases had significantly greater clinical attachment loss than controls (P=.04). After adjusting for important covariates, women diagnosed with periodontitis had two to three times higher odds of breast cancer than women without periodontitis depending on the case definition of periodontitis (P<.05). Conclusions: A significant association was observed between periodontitis and breast cancer.

Original languageEnglish (US)
Pages (from-to)545-551
Number of pages7
JournalCommunity Dentistry and Oral Epidemiology
Volume45
Issue number6
DOIs
StatePublished - Dec 1 2017

Fingerprint

Periodontitis
Case-Control Studies
Breast Neoplasms
International Classification of Diseases
Gynecology
Logistic Models
Smoking

Keywords

  • breast cancer
  • observational study
  • periodontal diseases
  • periodontitis
  • risk factors

ASJC Scopus subject areas

  • Dentistry(all)
  • Public Health, Environmental and Occupational Health

Cite this

Sfreddo, C. S., Maier, J., De David, S. C., Susin, C., & Moreira, C. H. C. (2017). Periodontitis and breast cancer: A case-control study. Community Dentistry and Oral Epidemiology, 45(6), 545-551. https://doi.org/10.1111/cdoe.12318

Periodontitis and breast cancer : A case-control study. / Sfreddo, Camila S.; Maier, Juliana; De David, Silvia C.; Susin, Cristiano; Moreira, Carlos Heitor C.

In: Community Dentistry and Oral Epidemiology, Vol. 45, No. 6, 01.12.2017, p. 545-551.

Research output: Contribution to journalArticle

Sfreddo, CS, Maier, J, De David, SC, Susin, C & Moreira, CHC 2017, 'Periodontitis and breast cancer: A case-control study', Community Dentistry and Oral Epidemiology, vol. 45, no. 6, pp. 545-551. https://doi.org/10.1111/cdoe.12318
Sfreddo CS, Maier J, De David SC, Susin C, Moreira CHC. Periodontitis and breast cancer: A case-control study. Community Dentistry and Oral Epidemiology. 2017 Dec 1;45(6):545-551. https://doi.org/10.1111/cdoe.12318
Sfreddo, Camila S. ; Maier, Juliana ; De David, Silvia C. ; Susin, Cristiano ; Moreira, Carlos Heitor C. / Periodontitis and breast cancer : A case-control study. In: Community Dentistry and Oral Epidemiology. 2017 ; Vol. 45, No. 6. pp. 545-551.
@article{9505a3c1028a4b188bcabb2072762957,
title = "Periodontitis and breast cancer: A case-control study",
abstract = "Objectives: The aim of this case-control study was to evaluate the association between periodontitis and breast cancer in a sample of adult Brazilian women. Methods: This was a hospital-based study, which included 67 cases and 134 controls (1:2). Women were selected consecutively between April, 2013 and June, 2015 among those attending the Department of Gynecology at the University Hospital of Santa Maria. Cases were selected among women diagnosed with breast cancer (ICD-10 C50), and controls were matched for age (±2 years), and smoking status (never, former and current smoker). Conditional logistic regression was used to model the association between periodontitis and breast cancer with and without adjustment for potential confounders. Four case definitions for periodontitis were used. Results: Cases had significantly greater clinical attachment loss than controls (P=.04). After adjusting for important covariates, women diagnosed with periodontitis had two to three times higher odds of breast cancer than women without periodontitis depending on the case definition of periodontitis (P<.05). Conclusions: A significant association was observed between periodontitis and breast cancer.",
keywords = "breast cancer, observational study, periodontal diseases, periodontitis, risk factors",
author = "Sfreddo, {Camila S.} and Juliana Maier and {De David}, {Silvia C.} and Cristiano Susin and Moreira, {Carlos Heitor C.}",
year = "2017",
month = "12",
day = "1",
doi = "10.1111/cdoe.12318",
language = "English (US)",
volume = "45",
pages = "545--551",
journal = "Community Dentistry and Oral Epidemiology",
issn = "0301-5661",
publisher = "Blackwell Munksgaard",
number = "6",

}

TY - JOUR

T1 - Periodontitis and breast cancer

T2 - A case-control study

AU - Sfreddo, Camila S.

AU - Maier, Juliana

AU - De David, Silvia C.

AU - Susin, Cristiano

AU - Moreira, Carlos Heitor C.

PY - 2017/12/1

Y1 - 2017/12/1

N2 - Objectives: The aim of this case-control study was to evaluate the association between periodontitis and breast cancer in a sample of adult Brazilian women. Methods: This was a hospital-based study, which included 67 cases and 134 controls (1:2). Women were selected consecutively between April, 2013 and June, 2015 among those attending the Department of Gynecology at the University Hospital of Santa Maria. Cases were selected among women diagnosed with breast cancer (ICD-10 C50), and controls were matched for age (±2 years), and smoking status (never, former and current smoker). Conditional logistic regression was used to model the association between periodontitis and breast cancer with and without adjustment for potential confounders. Four case definitions for periodontitis were used. Results: Cases had significantly greater clinical attachment loss than controls (P=.04). After adjusting for important covariates, women diagnosed with periodontitis had two to three times higher odds of breast cancer than women without periodontitis depending on the case definition of periodontitis (P<.05). Conclusions: A significant association was observed between periodontitis and breast cancer.

AB - Objectives: The aim of this case-control study was to evaluate the association between periodontitis and breast cancer in a sample of adult Brazilian women. Methods: This was a hospital-based study, which included 67 cases and 134 controls (1:2). Women were selected consecutively between April, 2013 and June, 2015 among those attending the Department of Gynecology at the University Hospital of Santa Maria. Cases were selected among women diagnosed with breast cancer (ICD-10 C50), and controls were matched for age (±2 years), and smoking status (never, former and current smoker). Conditional logistic regression was used to model the association between periodontitis and breast cancer with and without adjustment for potential confounders. Four case definitions for periodontitis were used. Results: Cases had significantly greater clinical attachment loss than controls (P=.04). After adjusting for important covariates, women diagnosed with periodontitis had two to three times higher odds of breast cancer than women without periodontitis depending on the case definition of periodontitis (P<.05). Conclusions: A significant association was observed between periodontitis and breast cancer.

KW - breast cancer

KW - observational study

KW - periodontal diseases

KW - periodontitis

KW - risk factors

UR - http://www.scopus.com/inward/record.url?scp=85033454410&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85033454410&partnerID=8YFLogxK

U2 - 10.1111/cdoe.12318

DO - 10.1111/cdoe.12318

M3 - Article

VL - 45

SP - 545

EP - 551

JO - Community Dentistry and Oral Epidemiology

JF - Community Dentistry and Oral Epidemiology

SN - 0301-5661

IS - 6

ER -