Periorbital vasculitis complicating Kawasaki syndrome in an infant.

M. W. Felz, A. Patni, S. E. Brooks, R. A. Tesser

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Periorbital vasculitis is a previously unreported complication of Kawasaki syndrome (KS). We describe an infant with severe KS refractory to initial management with salicylate and intravenous immunoglobulin (IVIG). Retreatment with IVIG and high-dose pulsed steroids was required for persistent fever and inflammatory manifestations. Despite aggressive medical therapy, a large left coronary artery aneurysm developed. After apparent complete KS remission, acute periorbital vasculitis developed in the left upper eyelid and orbit, requiring operative intervention for diagnosis and high-dose pulsed steroids for therapy. The significance of this previously unreported ophthalmic complication of KS is reviewed, along with a discussion of the role of steroids in KS manifestations refractory to IVIG.

Original languageEnglish (US)
JournalPediatrics
Volume101
Issue number6
StatePublished - Jun 1 1998

Fingerprint

Mucocutaneous Lymph Node Syndrome
Vasculitis
Intravenous Immunoglobulins
Steroids
Coronary Aneurysm
Retreatment
Salicylates
Orbit
Eyelids
Coronary Vessels
Fever
Therapeutics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Felz, M. W., Patni, A., Brooks, S. E., & Tesser, R. A. (1998). Periorbital vasculitis complicating Kawasaki syndrome in an infant. Pediatrics, 101(6).

Periorbital vasculitis complicating Kawasaki syndrome in an infant. / Felz, M. W.; Patni, A.; Brooks, S. E.; Tesser, R. A.

In: Pediatrics, Vol. 101, No. 6, 01.06.1998.

Research output: Contribution to journalArticle

Felz, MW, Patni, A, Brooks, SE & Tesser, RA 1998, 'Periorbital vasculitis complicating Kawasaki syndrome in an infant.', Pediatrics, vol. 101, no. 6.
Felz MW, Patni A, Brooks SE, Tesser RA. Periorbital vasculitis complicating Kawasaki syndrome in an infant. Pediatrics. 1998 Jun 1;101(6).
Felz, M. W. ; Patni, A. ; Brooks, S. E. ; Tesser, R. A. / Periorbital vasculitis complicating Kawasaki syndrome in an infant. In: Pediatrics. 1998 ; Vol. 101, No. 6.
@article{f9461658b4c846a58bf94836a407ea47,
title = "Periorbital vasculitis complicating Kawasaki syndrome in an infant.",
abstract = "Periorbital vasculitis is a previously unreported complication of Kawasaki syndrome (KS). We describe an infant with severe KS refractory to initial management with salicylate and intravenous immunoglobulin (IVIG). Retreatment with IVIG and high-dose pulsed steroids was required for persistent fever and inflammatory manifestations. Despite aggressive medical therapy, a large left coronary artery aneurysm developed. After apparent complete KS remission, acute periorbital vasculitis developed in the left upper eyelid and orbit, requiring operative intervention for diagnosis and high-dose pulsed steroids for therapy. The significance of this previously unreported ophthalmic complication of KS is reviewed, along with a discussion of the role of steroids in KS manifestations refractory to IVIG.",
author = "Felz, {M. W.} and A. Patni and Brooks, {S. E.} and Tesser, {R. A.}",
year = "1998",
month = "6",
day = "1",
language = "English (US)",
volume = "101",
journal = "Pediatrics",
issn = "0031-4005",
publisher = "American Academy of Pediatrics",
number = "6",

}

TY - JOUR

T1 - Periorbital vasculitis complicating Kawasaki syndrome in an infant.

AU - Felz, M. W.

AU - Patni, A.

AU - Brooks, S. E.

AU - Tesser, R. A.

PY - 1998/6/1

Y1 - 1998/6/1

N2 - Periorbital vasculitis is a previously unreported complication of Kawasaki syndrome (KS). We describe an infant with severe KS refractory to initial management with salicylate and intravenous immunoglobulin (IVIG). Retreatment with IVIG and high-dose pulsed steroids was required for persistent fever and inflammatory manifestations. Despite aggressive medical therapy, a large left coronary artery aneurysm developed. After apparent complete KS remission, acute periorbital vasculitis developed in the left upper eyelid and orbit, requiring operative intervention for diagnosis and high-dose pulsed steroids for therapy. The significance of this previously unreported ophthalmic complication of KS is reviewed, along with a discussion of the role of steroids in KS manifestations refractory to IVIG.

AB - Periorbital vasculitis is a previously unreported complication of Kawasaki syndrome (KS). We describe an infant with severe KS refractory to initial management with salicylate and intravenous immunoglobulin (IVIG). Retreatment with IVIG and high-dose pulsed steroids was required for persistent fever and inflammatory manifestations. Despite aggressive medical therapy, a large left coronary artery aneurysm developed. After apparent complete KS remission, acute periorbital vasculitis developed in the left upper eyelid and orbit, requiring operative intervention for diagnosis and high-dose pulsed steroids for therapy. The significance of this previously unreported ophthalmic complication of KS is reviewed, along with a discussion of the role of steroids in KS manifestations refractory to IVIG.

UR - http://www.scopus.com/inward/record.url?scp=0032091885&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032091885&partnerID=8YFLogxK

M3 - Article

C2 - 9606251

AN - SCOPUS:0032091885

VL - 101

JO - Pediatrics

JF - Pediatrics

SN - 0031-4005

IS - 6

ER -