Peripheral clocks and the regulation of cardiovascular and metabolic function

Radu Daniel Rudic, Anne M. Curtis, Yan Cheng, Garret FitzGerald

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Circadian rhythms generated by cell autonomous biological clocks allow for the appropriate temporal synchronization of physiology and behavior, optimizing the efficiency of biological systems. Circadian oscillators and functions have been uncovered in both central and peripheral tissues. This article describes methodology, experimental design, and technical challenges pertaining to studies of circadian rhythms in the periphery. Experimental approaches are focused upon revealing the role of peripheral clocks in cardiovascular and metabolic function using in vitro and in vivo techniques.

Original languageEnglish (US)
Article number27
Pages (from-to)524-539
Number of pages16
JournalMethods in Enzymology
Volume393
DOIs
StatePublished - Jan 1 2005
Externally publishedYes

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Circadian Rhythm
Clocks
Biological Clocks
Physiology
Biological systems
Design of experiments
Synchronization
Research Design
Tissue
In Vitro Techniques

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology

Cite this

Peripheral clocks and the regulation of cardiovascular and metabolic function. / Rudic, Radu Daniel; Curtis, Anne M.; Cheng, Yan; FitzGerald, Garret.

In: Methods in Enzymology, Vol. 393, 27, 01.01.2005, p. 524-539.

Research output: Contribution to journalArticle

Rudic, Radu Daniel ; Curtis, Anne M. ; Cheng, Yan ; FitzGerald, Garret. / Peripheral clocks and the regulation of cardiovascular and metabolic function. In: Methods in Enzymology. 2005 ; Vol. 393. pp. 524-539.
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