Phosphoric acid esters cannot replace polyvinylphosphonic acid as phosphoprotein analogs in biomimetic remineralization of resin-bonded dentin

Sui Mai, Young Kyung Kim, Manuel Toledano, Lorenzo Breschi, Jun Qi Ling, David Henry Pashley, Franklin Chi Meng Tay

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Polyvinylphosphonic acid (PVPA), a biomimetic analog of phosphoproteins, is crucial for recruiting polyacrylic acid (PAA)-stabilized amorphous calcium phosphate nanoprecursors during biomimetic remineralization of dentin collagen matrices. This study tested the null hypothesis that phosphoric acid esters of methacrylates in dentin adhesives cannot replace PVPA during bimimetic remineralization of resin-dentin interfaces. Human dentin specimens were bonded with: (I) XP Bond, an etch-and-rinse adhesive using moist bonding; (II) XP Bond using dry bonding; (III) Adper Prompt L-Pop, a self-etching adhesive. The control medium contained only set Portland cement and a simulated body fluid (SBF) without any biomimetic analog. Two experimental Portland cement/SBF remineralization media were evaluated: the first contained PAA as the sole biomimetic analog, the second contained PAA and PVPA as dual biomimetic analogs. No remineralization of the resin-dentin interfaces could be identified from specimens immersed in the control medium. After 2-4 months in the first experimental medium, specimens exhibited either no remineralization or large crystal formation within hybrid layers. Only specimens immersed in the second remineralization medium produced nanocrystals that accounted for intrafibrillar remineralization within hybrid layers. The null hypothesis could not be rejected; phosphoric acid esters in dentin adhesives cannot replace PVPA during biomimetic remineralization of adhesive-bonded dentin.

Original languageEnglish (US)
Pages (from-to)1230-1239
Number of pages10
JournalDental Materials
Volume25
Issue number10
DOIs
StatePublished - Oct 1 2009

Fingerprint

Biomimetics
Organophosphates
carbopol 940
Phosphoproteins
Phosphoric acid
Dentin
Esters
Resins
Adhesives
Acids
Body fluids
Portland cement
Body Fluids
Bond (masonry)
Methacrylates
Calcium phosphate
Nanocrystals
Etching
Collagen
Nanoparticles

Keywords

  • Biomimetics
  • Dentin adhesive
  • Interfibrillar
  • Intrafibrillar
  • Phosphate esters
  • Remineralization

ASJC Scopus subject areas

  • Materials Science(all)
  • Dentistry(all)
  • Mechanics of Materials

Cite this

Phosphoric acid esters cannot replace polyvinylphosphonic acid as phosphoprotein analogs in biomimetic remineralization of resin-bonded dentin. / Mai, Sui; Kim, Young Kyung; Toledano, Manuel; Breschi, Lorenzo; Ling, Jun Qi; Pashley, David Henry; Tay, Franklin Chi Meng.

In: Dental Materials, Vol. 25, No. 10, 01.10.2009, p. 1230-1239.

Research output: Contribution to journalArticle

Mai, Sui ; Kim, Young Kyung ; Toledano, Manuel ; Breschi, Lorenzo ; Ling, Jun Qi ; Pashley, David Henry ; Tay, Franklin Chi Meng. / Phosphoric acid esters cannot replace polyvinylphosphonic acid as phosphoprotein analogs in biomimetic remineralization of resin-bonded dentin. In: Dental Materials. 2009 ; Vol. 25, No. 10. pp. 1230-1239.
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