Physical training improves insulin resistance syndrome markers in obese adolescents

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Abstract

Introduction: The purpose of this study was to test the hypothesis that physical training (PT), especially high-intensity PT, would have a favorable effect on components of the insulin resistance syndrome (IRS) in obese adolescents. Methods: Obese 13- to 16-yr-olds (N = 80) were randomly assigned to one of the following 8-month interventions; 1) lifestyle education (LSE)-alone every 2 wk, 2) LSE+moderate-intensity PT, and 3) LSE+high-intensity PT. PT was offered 5 d·wk-1. Plasma triacylglycerol (TAG), total cholesterol (TC), high-density lipoprotein cholesterol (HDLC), very low-density lipoprotein cholesterol (VLDLC), low-density lipoprotein cholesterol (LDLC), low-density lipoprotein (low density lipoprotein (LDL)) particle size, apolipoproteins AI and B, glucose, insulin, and blood pressure were measured with standardized methods. Results: The intent-to-treat analyses for all subjects who completed preand post-tests regardless of their adherence to the interventions showed that the LSE+high-intensity PT group had more favorable changes than the LSE-alone group in TAG level (P = 0.012), TC/HDLC (P = 0.013), and diastolic blood pressure (P = 0.031). For efficacy analyses, all PT subjects who attended at least 2 d·wk-1 (40%) were combined into one group (LSE+PT) and compared with the LSE-alone group. These two-group analyses showed significant interactions (P < 0.001) between baseline values and group membership for ΔTAG, ΔVLDLC, and ΔTC/HDLC, such that subjects who had the least favorable baseline values showed the most beneficial impact of the PT. Of particular interest was a favorable effect of the PT on LDL particle size. Conclusion: PT, especially high-intensity PT, had a favorable effect on several IRS markers in obese adolescents.

Original languageEnglish (US)
Pages (from-to)1920-1927
Number of pages8
JournalMedicine and Science in Sports and Exercise
Volume34
Issue number12
DOIs
Publication statusPublished - Dec 1 2002

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Keywords

  • Body composition
  • Exercise
  • Insulin resistance syndrome
  • LDL particle size
  • Visceral adiposity

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Physical training improves insulin resistance syndrome markers in obese adolescents. / Kang, Hyun Sik; Gutin, Bernard; Barbeau, Paule; Owens, Scott; Lemmon, Christian R.; Allison, Jerry; Litaker, Mark S.; Le, Ngoc Anh.

In: Medicine and Science in Sports and Exercise, Vol. 34, No. 12, 01.12.2002, p. 1920-1927.

Research output: Contribution to journalArticle