Abstract
A cross-transmission outbreak of gentamicin-resistant Serratia marcescens infection, followed by smaller outbreaks of gentamicin-resistant Klebsiella pneumoniae and Providentia rettgeri infection, occurred in a Veterans Administration hospital that was in the process of becoming a major teaching hospital within a new medical school. The resistant Serratia isolates carried a single plasmid, which was found only occasionally in other gentamicin-resistant bacterial species. Amikacin-resistant Serratia marcescens emerged despite infrequent use of amikacin. Environmental contamination with gentamicin-resistant Serratia was documented, in one instance, on the day following transfer of all patients in the hospital to a new facility. Control measures were thought to be responsible, at least in part, for the eventual decline in frequency of gentamicin-resistant bacteria.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 65-71 |
| Number of pages | 7 |
| Journal | American Journal of Infection Control |
| Volume | 8 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jan 1 1980 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Epidemiology
- Health Policy
- Public Health, Environmental and Occupational Health
- Infectious Diseases
Cite this
Plasmid-mediated antibiotic resistance in a changing hospital environment : Efficacy of control measures. / Bryan, Charles S.; Parker, Ellen; Schoenlein, Patricia V; Northey, Jimmie; Ely, Bert; John, Joseph F.
In: American Journal of Infection Control, Vol. 8, No. 3, 01.01.1980, p. 65-71.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Plasmid-mediated antibiotic resistance in a changing hospital environment
T2 - Efficacy of control measures
AU - Bryan, Charles S.
AU - Parker, Ellen
AU - Schoenlein, Patricia V
AU - Northey, Jimmie
AU - Ely, Bert
AU - John, Joseph F.
PY - 1980/1/1
Y1 - 1980/1/1
N2 - A cross-transmission outbreak of gentamicin-resistant Serratia marcescens infection, followed by smaller outbreaks of gentamicin-resistant Klebsiella pneumoniae and Providentia rettgeri infection, occurred in a Veterans Administration hospital that was in the process of becoming a major teaching hospital within a new medical school. The resistant Serratia isolates carried a single plasmid, which was found only occasionally in other gentamicin-resistant bacterial species. Amikacin-resistant Serratia marcescens emerged despite infrequent use of amikacin. Environmental contamination with gentamicin-resistant Serratia was documented, in one instance, on the day following transfer of all patients in the hospital to a new facility. Control measures were thought to be responsible, at least in part, for the eventual decline in frequency of gentamicin-resistant bacteria.
AB - A cross-transmission outbreak of gentamicin-resistant Serratia marcescens infection, followed by smaller outbreaks of gentamicin-resistant Klebsiella pneumoniae and Providentia rettgeri infection, occurred in a Veterans Administration hospital that was in the process of becoming a major teaching hospital within a new medical school. The resistant Serratia isolates carried a single plasmid, which was found only occasionally in other gentamicin-resistant bacterial species. Amikacin-resistant Serratia marcescens emerged despite infrequent use of amikacin. Environmental contamination with gentamicin-resistant Serratia was documented, in one instance, on the day following transfer of all patients in the hospital to a new facility. Control measures were thought to be responsible, at least in part, for the eventual decline in frequency of gentamicin-resistant bacteria.
UR - http://www.scopus.com/inward/record.url?scp=84908717075&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84908717075&partnerID=8YFLogxK
U2 - 10.1016/S0196-6553(80)80026-5
DO - 10.1016/S0196-6553(80)80026-5
M3 - Article
VL - 8
SP - 65
EP - 71
JO - American Journal of Infection Control
JF - American Journal of Infection Control
SN - 0196-6553
IS - 3
ER -