Pneumocystis colonization in asthmatic patients not receiving oral corticosteroid therapy

Emma L. Davey, Rhonda E. Colombo, Charles Fiorentino, Gary Fahle, Richard T. Davey, Kenneth N. Olivier, Joseph A. Kovacs

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Pneumocystis jirovecii can colonize patients with chronic obstructive pulmonary disease. To determine if colonization occurs in asthma patients, sputum samples from 10 patients with mild asthma, who were not receiving oral corticosteroids, were evaluated by a sensitive real-time PCR assay that targets a multicopy gene of P. jirovecii. 2 patients (20%) had Pneumocystis DNA detected; 1 patient had 3 positive samples over an 11-day period. Thus, Pneumocystis colonization occurs in asthma patients, and further studies are warranted to evaluate its role in airways disease.

Original languageEnglish (US)
Pages (from-to)800-802
Number of pages3
JournalJournal of Investigative Medicine
Volume65
Issue number4
DOIs
StatePublished - Apr 2017

Keywords

  • Asthma
  • Lung Diseases

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Davey, E. L., Colombo, R. E., Fiorentino, C., Fahle, G., Davey, R. T., Olivier, K. N., & Kovacs, J. A. (2017). Pneumocystis colonization in asthmatic patients not receiving oral corticosteroid therapy. Journal of Investigative Medicine, 65(4), 800-802. https://doi.org/10.1136/jim-2016-000381