Polyethylene glycol (PEG) hydrogel dural sealant and collagen dural graft matrix in transsphenoidal pituitary surgery for prevention of postoperative cerebrospinal fluid leaks

Clinton J. Burkett, Samip Patel, Mark H. Tabor, Tapan Padhya, Fernando Vale Diaz

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Cerebrospinal fluid (CSF) rhinorrhea is the most common complication after transsphenoidal pituitary surgery. The authors compare their previous experience using an autologous fat graft and lumbar drain placement in 107 patients with their current technique of using a dural sealant and collagen matrix in 97 patients to prevent postoperative CSF leak after pituitary tumor resection. The failure rate for CSF leak repairs between the two groups was similar. The use of a dural sealant and collagen matrix, however, has the advantages of decreased length of hospital stay, decreased length of Intensive Care Unit stay, avoidance of the morbidity of an extra abdominal incision, and avoidance of the risks of lumbar CSF drainage.

Original languageEnglish (US)
Pages (from-to)1513-1517
Number of pages5
JournalJournal of Clinical Neuroscience
Volume18
Issue number11
DOIs
StatePublished - Nov 1 2011

Fingerprint

Hydrogel
Collagen
Transplants
Length of Stay
Cerebrospinal Fluid Rhinorrhea
Pituitary Neoplasms
Intensive Care Units
Fats
Morbidity
Cerebrospinal Fluid Leak

Keywords

  • CSF leak
  • Dural sealant
  • Pituitary tumors
  • Transsphenoidal surgery

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

Cite this

Polyethylene glycol (PEG) hydrogel dural sealant and collagen dural graft matrix in transsphenoidal pituitary surgery for prevention of postoperative cerebrospinal fluid leaks. / Burkett, Clinton J.; Patel, Samip; Tabor, Mark H.; Padhya, Tapan; Vale Diaz, Fernando.

In: Journal of Clinical Neuroscience, Vol. 18, No. 11, 01.11.2011, p. 1513-1517.

Research output: Contribution to journalArticle

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