Polyspermy: Effect of varying stimulation protocols and inseminating sperm concentrations

Michael Peter Diamond; B. J. Rogers; B. W. Webster; W. K. Vaughn; A. C. Wentz

doi:10.1016/S0015-0282(16)48565-1

Polyspermy: Effect of varying stimulation protocols and inseminating sperm concentrations

Michael Peter Diamond, B. J. Rogers, B. W. Webster, W. K. Vaughn, A. C. Wentz

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Results from 198 cycles of in vitro fertilization (IVF) were examined to identify factors in the subsequent development of polyspermy. Polyspermy occurred in 24 of 235 fertilized oocytes and was equally likely in mature and immature oocytes. No significant difference in polyspermy was demonstrated between the stimulation protocol using human menopausal gonadotropin (hMG) and those using clomiphene citrate (CC) or combined hMG/CC. The incidence of polyspermy was no different after insemination of oocytes with concentrations of progressively motile sperm ranging from 250,000 to 500,000. Although polyspermy continues to be a problem in IVF, we have been unable to identify possible predisposing mechanisms for its development.

Original language	English (US)
Pages (from-to)	777-780
Number of pages	4
Journal	Fertility and sterility
Volume	43
Issue number	5
DOIs	https://doi.org/10.1016/S0015-0282(16)48565-1
State	Published - 1985
Externally published	Yes

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

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title = "Polyspermy: Effect of varying stimulation protocols and inseminating sperm concentrations",

abstract = "Results from 198 cycles of in vitro fertilization (IVF) were examined to identify factors in the subsequent development of polyspermy. Polyspermy occurred in 24 of 235 fertilized oocytes and was equally likely in mature and immature oocytes. No significant difference in polyspermy was demonstrated between the stimulation protocol using human menopausal gonadotropin (hMG) and those using clomiphene citrate (CC) or combined hMG/CC. The incidence of polyspermy was no different after insemination of oocytes with concentrations of progressively motile sperm ranging from 250,000 to 500,000. Although polyspermy continues to be a problem in IVF, we have been unable to identify possible predisposing mechanisms for its development.",

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T1 - Polyspermy

T2 - Effect of varying stimulation protocols and inseminating sperm concentrations

AU - Diamond, Michael Peter

AU - Rogers, B. J.

AU - Webster, B. W.

AU - Vaughn, W. K.

AU - Wentz, A. C.

PY - 1985

Y1 - 1985

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AB - Results from 198 cycles of in vitro fertilization (IVF) were examined to identify factors in the subsequent development of polyspermy. Polyspermy occurred in 24 of 235 fertilized oocytes and was equally likely in mature and immature oocytes. No significant difference in polyspermy was demonstrated between the stimulation protocol using human menopausal gonadotropin (hMG) and those using clomiphene citrate (CC) or combined hMG/CC. The incidence of polyspermy was no different after insemination of oocytes with concentrations of progressively motile sperm ranging from 250,000 to 500,000. Although polyspermy continues to be a problem in IVF, we have been unable to identify possible predisposing mechanisms for its development.

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Polyspermy: Effect of varying stimulation protocols and inseminating sperm concentrations

Abstract

ASJC Scopus subject areas

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