Polyspermy

Effect of varying stimulation protocols and inseminating sperm concentrations

Michael Peter Diamond, B. J. Rogers, B. W. Webster, W. K. Vaughn, A. C. Wentz

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Results from 198 cycles of in vitro fertilization (IVF) were examined to identify factors in the subsequent development of polyspermy. Polyspermy occurred in 24 of 235 fertilized oocytes and was equally likely in mature and immature oocytes. No significant difference in polyspermy was demonstrated between the stimulation protocol using human menopausal gonadotropin (hMG) and those using clomiphene citrate (CC) or combined hMG/CC. The incidence of polyspermy was no different after insemination of oocytes with concentrations of progressively motile sperm ranging from 250,000 to 500,000. Although polyspermy continues to be a problem in IVF, we have been unable to identify possible predisposing mechanisms for its development.

Original languageEnglish (US)
Pages (from-to)777-780
Number of pages4
JournalFertility and Sterility
Volume43
Issue number5
DOIs
StatePublished - Jan 1 1985
Externally publishedYes

Fingerprint

Menotropins
Oocytes
Spermatozoa
Clomiphene
Fertilization in Vitro
Insemination
Incidence

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

Cite this

Polyspermy : Effect of varying stimulation protocols and inseminating sperm concentrations. / Diamond, Michael Peter; Rogers, B. J.; Webster, B. W.; Vaughn, W. K.; Wentz, A. C.

In: Fertility and Sterility, Vol. 43, No. 5, 01.01.1985, p. 777-780.

Research output: Contribution to journalArticle

Diamond, Michael Peter ; Rogers, B. J. ; Webster, B. W. ; Vaughn, W. K. ; Wentz, A. C. / Polyspermy : Effect of varying stimulation protocols and inseminating sperm concentrations. In: Fertility and Sterility. 1985 ; Vol. 43, No. 5. pp. 777-780.
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