Population genetic analysis of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China

Bo Feng Zhu, Guang Yang, Chun Mei Shen, Hai Xia Qin, Shuan Liang Fan, Li Bin Deng, Feng Chen, Li Ping Chen, Hong Dan Wang, Zhen Yuan Wang, Rudolf Lucas, Zhen Min Lian

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

In the present study, we investigated the genetic polymorphisms of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China as well as its genetic relationships with other populations. DNA typing for 15 autosomal STR loci was performed on 148 randomly selected healthy individuals from the Russian population living in Eerguna, northeastern Inner-Mongolia. Allelic frequencies of these loci were calculated by direct counting. The genotype data of this Russian population was moreover compared to other populations using neighbor-joining method, as such constructing a phylogenic tree. A total of 143 alleles were found in the Russian population with corresponding allele frequencies in the range from 0.0034 to 0.5372. Among all the 15 loci, D18S51 had the highest polymorphism (PIC = 0.8632), whereas TPOX had the lowest (PIC = 0.5179). In the phylogenic tree, this Russian population has a close relationship with the populations of South Siberia and northeastern Asia. This study may increase our understanding of the genetic background of the Russian population in Eerguna, China as such providing useful information for anthropological research, forensic sciences as well as disease-association studies.

Original languageEnglish (US)
Pages (from-to)3889-3895
Number of pages7
JournalMolecular Biology Reports
Volume37
Issue number8
DOIs
StatePublished - Dec 1 2010

Keywords

  • Population genetics
  • Russian population
  • STR

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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    Zhu, B. F., Yang, G., Shen, C. M., Qin, H. X., Fan, S. L., Deng, L. B., Chen, F., Chen, L. P., Wang, H. D., Wang, Z. Y., Lucas, R., & Lian, Z. M. (2010). Population genetic analysis of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China. Molecular Biology Reports, 37(8), 3889-3895. https://doi.org/10.1007/s11033-010-0045-y