Posterior Parietal Cortex Encodes Autonomously Selected Motor Plans

He Cui, Richard A. Andersen

Research output: Contribution to journalArticle

142 Citations (Scopus)

Abstract

The posterior parietal cortex (PPC) of rhesus monkeys has been found to encode the behavioral meaning of categories of sensory stimuli. When animals are instructed with sensory cues to make either eye or hand movements to a target, PPC cells also show specificity depending on which effector (eye or hand) is instructed for the movement. To determine whether this selectivity retrospectively reflects the behavioral meaning of the cue or prospectively encodes the movement plan, we trained monkeys to autonomously choose to acquire a target in the absence of direct instructions specifying which effector to use. Activity in PPC showed strong specificity for effector choice, with cells in the lateral intraparietal area selective for saccades and cells in the parietal reach region selective for reaches. Such differential activity associated with effector choice under identical stimulus conditions provides definitive evidence that the PPC is prospectively involved in action selection and movement preparation.

Original languageEnglish (US)
Pages (from-to)552-559
Number of pages8
JournalNeuron
Volume56
Issue number3
DOIs
StatePublished - Nov 8 2007

Fingerprint

Parietal Lobe
Cues
Hand
Saccades
Macaca mulatta
Haplorhini

Keywords

  • SYSNEURO

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Posterior Parietal Cortex Encodes Autonomously Selected Motor Plans. / Cui, He; Andersen, Richard A.

In: Neuron, Vol. 56, No. 3, 08.11.2007, p. 552-559.

Research output: Contribution to journalArticle

Cui, He ; Andersen, Richard A. / Posterior Parietal Cortex Encodes Autonomously Selected Motor Plans. In: Neuron. 2007 ; Vol. 56, No. 3. pp. 552-559.
@article{859250b1be5341a7a93e8640aeaa573d,
title = "Posterior Parietal Cortex Encodes Autonomously Selected Motor Plans",
abstract = "The posterior parietal cortex (PPC) of rhesus monkeys has been found to encode the behavioral meaning of categories of sensory stimuli. When animals are instructed with sensory cues to make either eye or hand movements to a target, PPC cells also show specificity depending on which effector (eye or hand) is instructed for the movement. To determine whether this selectivity retrospectively reflects the behavioral meaning of the cue or prospectively encodes the movement plan, we trained monkeys to autonomously choose to acquire a target in the absence of direct instructions specifying which effector to use. Activity in PPC showed strong specificity for effector choice, with cells in the lateral intraparietal area selective for saccades and cells in the parietal reach region selective for reaches. Such differential activity associated with effector choice under identical stimulus conditions provides definitive evidence that the PPC is prospectively involved in action selection and movement preparation.",
keywords = "SYSNEURO",
author = "He Cui and Andersen, {Richard A.}",
year = "2007",
month = "11",
day = "8",
doi = "10.1016/j.neuron.2007.09.031",
language = "English (US)",
volume = "56",
pages = "552--559",
journal = "Neuron",
issn = "0896-6273",
publisher = "Cell Press",
number = "3",

}

TY - JOUR

T1 - Posterior Parietal Cortex Encodes Autonomously Selected Motor Plans

AU - Cui, He

AU - Andersen, Richard A.

PY - 2007/11/8

Y1 - 2007/11/8

N2 - The posterior parietal cortex (PPC) of rhesus monkeys has been found to encode the behavioral meaning of categories of sensory stimuli. When animals are instructed with sensory cues to make either eye or hand movements to a target, PPC cells also show specificity depending on which effector (eye or hand) is instructed for the movement. To determine whether this selectivity retrospectively reflects the behavioral meaning of the cue or prospectively encodes the movement plan, we trained monkeys to autonomously choose to acquire a target in the absence of direct instructions specifying which effector to use. Activity in PPC showed strong specificity for effector choice, with cells in the lateral intraparietal area selective for saccades and cells in the parietal reach region selective for reaches. Such differential activity associated with effector choice under identical stimulus conditions provides definitive evidence that the PPC is prospectively involved in action selection and movement preparation.

AB - The posterior parietal cortex (PPC) of rhesus monkeys has been found to encode the behavioral meaning of categories of sensory stimuli. When animals are instructed with sensory cues to make either eye or hand movements to a target, PPC cells also show specificity depending on which effector (eye or hand) is instructed for the movement. To determine whether this selectivity retrospectively reflects the behavioral meaning of the cue or prospectively encodes the movement plan, we trained monkeys to autonomously choose to acquire a target in the absence of direct instructions specifying which effector to use. Activity in PPC showed strong specificity for effector choice, with cells in the lateral intraparietal area selective for saccades and cells in the parietal reach region selective for reaches. Such differential activity associated with effector choice under identical stimulus conditions provides definitive evidence that the PPC is prospectively involved in action selection and movement preparation.

KW - SYSNEURO

UR - http://www.scopus.com/inward/record.url?scp=35648930943&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=35648930943&partnerID=8YFLogxK

U2 - 10.1016/j.neuron.2007.09.031

DO - 10.1016/j.neuron.2007.09.031

M3 - Article

C2 - 17988637

AN - SCOPUS:35648930943

VL - 56

SP - 552

EP - 559

JO - Neuron

JF - Neuron

SN - 0896-6273

IS - 3

ER -