Persistent vascular deposition of immunoglobulin and complement indicates irreversible vasculitis and impending graft loss. Peripheral blood helper/suppressor cell ratios are not predictive of graft rejection in patients treated with cyclosporin-A and prednisone. Allograft rejection is accompanied by tissue infiltration with OKT8+ lymphocytes. Natural killer cells and monocytes do not appear to be important in rejection of cardiac allografts.
|Original language||English (US)|
|Number of pages||2|
|State||Published - Jan 1 1983|
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