The aim of the study was to investigate the use of granulocyte macrophage-colony stimulating factor (GM-CSF) as an adjunctive treatment for clinically refractory mucosal candidiasis in patients with advanced AIDS. Three patients with advanced AIDS and oropharyngeal candidiasis clinically refractory to azoles or amphotericin B received GM-CSF for 14 days along with either fluconazole or amphotericin B. All three patients showed clinical improvement and mycological improvement without any adverse events. Thus, GM-CSF may be a possible alternative as adjunctive therapy in the management of refractory mucosal candidiasis in patients with advanced AIDS.
|Original language||English (US)|
|Number of pages||3|
|Journal||European Journal of Clinical Microbiology and Infectious Diseases|
|Publication status||Published - Dec 1 1998|
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases