Practice parameters for the treatment of narcolepsy: An update for 2000

M. Littner, S. F. Johnson, William Vaughn McCall, W. McDowell Anderson, D. Davila, K. Hartse, C. A. Kushida, M. S. Wise, M. Hirshkowitz, B. T. Woodson

Research output: Contribution to journalArticle

128 Citations (Scopus)

Abstract

Successful treatment of narcolepsy requires an accurate diagnosis to exclude patients with other sleep disorders, which have different treatments, and to avoid unnecessary complications of drug treatment. Treatment objectives should be tailored to individual circumstances. Modafinil, amphetamine, methamphetamine, dextroamphetamine, methylphenidate, selegiline, pemoline, tricyclic antidepressants, and fluoxetine are effective treatments for narcolepsy, but the quality of published clinical evidence supporting them varies. Scheduled naps can be beneficial to combat sleepiness, but naps seldom suffice as primary therapy. Regular follow up of patients with narcolepsy is necessary to educate patients and their families, monitor for complications of therapy and emergent of other sleep disorders, and help the patient adapt to the disease.

Original languageEnglish (US)
Pages (from-to)451-466
Number of pages16
JournalSleep
Volume24
Issue number4
StatePublished - Jun 15 2001

Fingerprint

Narcolepsy
Therapeutics
Pemoline
Selegiline
Dextroamphetamine
Methylphenidate
Methamphetamine
Tricyclic Antidepressive Agents
Fluoxetine
Amphetamine
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology (medical)

Cite this

Littner, M., Johnson, S. F., McCall, W. V., McDowell Anderson, W., Davila, D., Hartse, K., ... Woodson, B. T. (2001). Practice parameters for the treatment of narcolepsy: An update for 2000. Sleep, 24(4), 451-466.

Practice parameters for the treatment of narcolepsy : An update for 2000. / Littner, M.; Johnson, S. F.; McCall, William Vaughn; McDowell Anderson, W.; Davila, D.; Hartse, K.; Kushida, C. A.; Wise, M. S.; Hirshkowitz, M.; Woodson, B. T.

In: Sleep, Vol. 24, No. 4, 15.06.2001, p. 451-466.

Research output: Contribution to journalArticle

Littner, M, Johnson, SF, McCall, WV, McDowell Anderson, W, Davila, D, Hartse, K, Kushida, CA, Wise, MS, Hirshkowitz, M & Woodson, BT 2001, 'Practice parameters for the treatment of narcolepsy: An update for 2000', Sleep, vol. 24, no. 4, pp. 451-466.
Littner M, Johnson SF, McCall WV, McDowell Anderson W, Davila D, Hartse K et al. Practice parameters for the treatment of narcolepsy: An update for 2000. Sleep. 2001 Jun 15;24(4):451-466.
Littner, M. ; Johnson, S. F. ; McCall, William Vaughn ; McDowell Anderson, W. ; Davila, D. ; Hartse, K. ; Kushida, C. A. ; Wise, M. S. ; Hirshkowitz, M. ; Woodson, B. T. / Practice parameters for the treatment of narcolepsy : An update for 2000. In: Sleep. 2001 ; Vol. 24, No. 4. pp. 451-466.
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