Practice parameters for the treatment of narcolepsy: An update for 2000

M. Littner, S. F. Johnson, W. V. McCall, W. McDowell Anderson, D. Davila, K. Hartse, C. A. Kushida, M. S. Wise, M. Hirshkowitz, B. T. Woodson

Research output: Contribution to journalArticle

130 Scopus citations

Abstract

Successful treatment of narcolepsy requires an accurate diagnosis to exclude patients with other sleep disorders, which have different treatments, and to avoid unnecessary complications of drug treatment. Treatment objectives should be tailored to individual circumstances. Modafinil, amphetamine, methamphetamine, dextroamphetamine, methylphenidate, selegiline, pemoline, tricyclic antidepressants, and fluoxetine are effective treatments for narcolepsy, but the quality of published clinical evidence supporting them varies. Scheduled naps can be beneficial to combat sleepiness, but naps seldom suffice as primary therapy. Regular follow up of patients with narcolepsy is necessary to educate patients and their families, monitor for complications of therapy and emergent of other sleep disorders, and help the patient adapt to the disease.

Original languageEnglish (US)
Pages (from-to)451-466
Number of pages16
JournalSleep
Volume24
Issue number4
StatePublished - Jun 15 2001
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology (medical)

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    Littner, M., Johnson, S. F., McCall, W. V., McDowell Anderson, W., Davila, D., Hartse, K., Kushida, C. A., Wise, M. S., Hirshkowitz, M., & Woodson, B. T. (2001). Practice parameters for the treatment of narcolepsy: An update for 2000. Sleep, 24(4), 451-466.