Prediction of left ventricular mass in youth with family histories of essential hypertension

Kenneth A Murdison, Frank A. Treiber, George Mensah, Harry Davis, William Thompson, William B. Strong

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

To determine predictors of left ventricular mass (LVM) and hypertrophy (LVH), 56 black and 30 white normotensive healthy youths (mean age 12.6 ± 2.3 years at initial visit) were studied twice, 2.5 years apart. During the initial visit, anthropometric variables and hemodynamics were measured at rest and before, during, and after 4 physical and behavioral stressors. 2-D directed M-mode echocardiography was performed to derive LVM. Hierarchical multiple regression analyses indicated that follow-up LVM was predicted by initial LVM, weight, height (ht), and gender (males > females; total model R2 = 0.77, P < 0.0001). Predictors of LVM/ht2.7 were initial LVM/ht2.7, weight, ethnicity (blacks > whites), and the aggregate index of blood pressure reactivity (total model R2 = 0.66, P < 0.0001). Youth with LVH at follow-up were taller, heavier, and exhibited greater blood pressure reactivity at initial evaluation. These findings are important since interventional strategies can be developed that target obesity and exaggerated reactivity to stress.

Original languageEnglish (US)
Pages (from-to)118-123
Number of pages6
JournalAmerican Journal of the Medical Sciences
Volume315
Issue number2
DOIs
StatePublished - Jan 1 1998

Fingerprint

Blood Pressure
Left Ventricular Hypertrophy
Hypertrophy
Echocardiography
Obesity
Hemodynamics
Regression Analysis
Weights and Measures
Essential Hypertension
hydroquinone

Keywords

  • Cardiovascular reactivity
  • Left ventricular mass
  • Prediction

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Prediction of left ventricular mass in youth with family histories of essential hypertension. / Murdison, Kenneth A; Treiber, Frank A.; Mensah, George; Davis, Harry; Thompson, William; Strong, William B.

In: American Journal of the Medical Sciences, Vol. 315, No. 2, 01.01.1998, p. 118-123.

Research output: Contribution to journalArticle

Murdison, Kenneth A ; Treiber, Frank A. ; Mensah, George ; Davis, Harry ; Thompson, William ; Strong, William B. / Prediction of left ventricular mass in youth with family histories of essential hypertension. In: American Journal of the Medical Sciences. 1998 ; Vol. 315, No. 2. pp. 118-123.
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