Preliminary investigation of the dosimetric properties of 'RadGel'

Joseph R Newton, A. Thomas, A. Appleby, C. Marsden, E. A. Christman, J. G. Wolodzko, M. Oldham

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A preliminary investigation into the efficacy of a new 3D dosimetry material, RadGel™, for verification of radiation therapy dose distributions is presented. Small volumes of RadGel™ were found to exhibit a linear, reproducible response to dose. A gradual increase in optical-density (OD) with time was observed, suggesting scanning should be completed within 18 hours to keep a linear correlation of R2 > 0.99. A larger 10 cm diameter volume of RadGel™ was irradiated with a rotationally symmetric "spoke" plan designed to rigorously evaluate scanner/dosimeter combined performance. The dosimeter was imaged with the Duke Mid-sized Optical-CT Scanner (DMOS). Promising OD and corresponding dose maps were obtained. Edge artefacts were observed and are suspected to be exacerbated by the particular container used in this early study. Further studies will evaluate new containers and methods for refractive matching at the gel-container-fluid interface.

Original languageEnglish (US)
Article number012011
Pages (from-to)49-53
Number of pages5
JournalJournal of Physics: Conference Series
Volume250
DOIs
StatePublished - Jan 1 2010

Fingerprint

containers
dosimeters
optical density
dosage
scanners
spokes
artifacts
radiation therapy
gels
scanning
fluids

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Newton, J. R., Thomas, A., Appleby, A., Marsden, C., Christman, E. A., Wolodzko, J. G., & Oldham, M. (2010). Preliminary investigation of the dosimetric properties of 'RadGel'. Journal of Physics: Conference Series, 250, 49-53. [012011]. https://doi.org/10.1088/1742-6596/250/1/012011

Preliminary investigation of the dosimetric properties of 'RadGel'. / Newton, Joseph R; Thomas, A.; Appleby, A.; Marsden, C.; Christman, E. A.; Wolodzko, J. G.; Oldham, M.

In: Journal of Physics: Conference Series, Vol. 250, 012011, 01.01.2010, p. 49-53.

Research output: Contribution to journalArticle

Newton, JR, Thomas, A, Appleby, A, Marsden, C, Christman, EA, Wolodzko, JG & Oldham, M 2010, 'Preliminary investigation of the dosimetric properties of 'RadGel'', Journal of Physics: Conference Series, vol. 250, 012011, pp. 49-53. https://doi.org/10.1088/1742-6596/250/1/012011
Newton, Joseph R ; Thomas, A. ; Appleby, A. ; Marsden, C. ; Christman, E. A. ; Wolodzko, J. G. ; Oldham, M. / Preliminary investigation of the dosimetric properties of 'RadGel'. In: Journal of Physics: Conference Series. 2010 ; Vol. 250. pp. 49-53.
@article{7c4b265dd9dc4068932aa7575f119aa5,
title = "Preliminary investigation of the dosimetric properties of 'RadGel'",
abstract = "A preliminary investigation into the efficacy of a new 3D dosimetry material, RadGel™, for verification of radiation therapy dose distributions is presented. Small volumes of RadGel™ were found to exhibit a linear, reproducible response to dose. A gradual increase in optical-density (OD) with time was observed, suggesting scanning should be completed within 18 hours to keep a linear correlation of R2 > 0.99. A larger 10 cm diameter volume of RadGel™ was irradiated with a rotationally symmetric {"}spoke{"} plan designed to rigorously evaluate scanner/dosimeter combined performance. The dosimeter was imaged with the Duke Mid-sized Optical-CT Scanner (DMOS). Promising OD and corresponding dose maps were obtained. Edge artefacts were observed and are suspected to be exacerbated by the particular container used in this early study. Further studies will evaluate new containers and methods for refractive matching at the gel-container-fluid interface.",
author = "Newton, {Joseph R} and A. Thomas and A. Appleby and C. Marsden and Christman, {E. A.} and Wolodzko, {J. G.} and M. Oldham",
year = "2010",
month = "1",
day = "1",
doi = "10.1088/1742-6596/250/1/012011",
language = "English (US)",
volume = "250",
pages = "49--53",
journal = "Journal of Physics: Conference Series",
issn = "1742-6588",
publisher = "IOP Publishing Ltd.",

}

TY - JOUR

T1 - Preliminary investigation of the dosimetric properties of 'RadGel'

AU - Newton, Joseph R

AU - Thomas, A.

AU - Appleby, A.

AU - Marsden, C.

AU - Christman, E. A.

AU - Wolodzko, J. G.

AU - Oldham, M.

PY - 2010/1/1

Y1 - 2010/1/1

N2 - A preliminary investigation into the efficacy of a new 3D dosimetry material, RadGel™, for verification of radiation therapy dose distributions is presented. Small volumes of RadGel™ were found to exhibit a linear, reproducible response to dose. A gradual increase in optical-density (OD) with time was observed, suggesting scanning should be completed within 18 hours to keep a linear correlation of R2 > 0.99. A larger 10 cm diameter volume of RadGel™ was irradiated with a rotationally symmetric "spoke" plan designed to rigorously evaluate scanner/dosimeter combined performance. The dosimeter was imaged with the Duke Mid-sized Optical-CT Scanner (DMOS). Promising OD and corresponding dose maps were obtained. Edge artefacts were observed and are suspected to be exacerbated by the particular container used in this early study. Further studies will evaluate new containers and methods for refractive matching at the gel-container-fluid interface.

AB - A preliminary investigation into the efficacy of a new 3D dosimetry material, RadGel™, for verification of radiation therapy dose distributions is presented. Small volumes of RadGel™ were found to exhibit a linear, reproducible response to dose. A gradual increase in optical-density (OD) with time was observed, suggesting scanning should be completed within 18 hours to keep a linear correlation of R2 > 0.99. A larger 10 cm diameter volume of RadGel™ was irradiated with a rotationally symmetric "spoke" plan designed to rigorously evaluate scanner/dosimeter combined performance. The dosimeter was imaged with the Duke Mid-sized Optical-CT Scanner (DMOS). Promising OD and corresponding dose maps were obtained. Edge artefacts were observed and are suspected to be exacerbated by the particular container used in this early study. Further studies will evaluate new containers and methods for refractive matching at the gel-container-fluid interface.

UR - http://www.scopus.com/inward/record.url?scp=78650554132&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78650554132&partnerID=8YFLogxK

U2 - 10.1088/1742-6596/250/1/012011

DO - 10.1088/1742-6596/250/1/012011

M3 - Article

VL - 250

SP - 49

EP - 53

JO - Journal of Physics: Conference Series

JF - Journal of Physics: Conference Series

SN - 1742-6588

M1 - 012011

ER -