Presentations of acute phenytoin overdose

Larry B. Mellick, J. Alan Morgan, Gary A. Mellick

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

A 15-year-old boy ingested 19.6 g (15 g veriflable) phenytoin sodium approximately four hours before emergency department presentation. The patient survived the suicide attempt with only supportive care, despite the ingestion of 392 mg/kg and a peak serum level of 100.8 μg/mL. A wide spectrum of physical findings consistent with acute massive ingestion of phenytoin was noted. This case report and a review of cases reported in the English literature of acute single anticonvulsant ingestion further delineate the clinical presentation of acute phenytoin overdose.

Original languageEnglish (US)
Pages (from-to)61-67
Number of pages7
JournalAmerican Journal of Emergency Medicine
Volume7
Issue number1
DOIs
StatePublished - Jan 1989

Keywords

  • Phenytoin
  • anticonvulsant overdose

ASJC Scopus subject areas

  • Emergency Medicine

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